Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 9/20 | 0.43 |
| ▸ | TSPO | P30536 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362477 | 0.94 | CRHR1 (0.47) | KDM4ECRHR1 | |
| Trifluoroacetic Acid SCHEMBL4698869 | 0.93 | KDM4E (0.40) | KDM4ECRHR1TSPOLMNATSHR | |
| SCHEMBL3366121 | 0.92 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL3364610 | 0.92 | CRHR1 (0.49) | KDM4ECRHR1 | |
| SCHEMBL3367997 | 0.89 | CRHR1 (0.44) | KDM4ECRHR1TSPOLMNATSHR | |
| SCHEMBL3364735 | 0.89 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL4699539 | 0.85 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL3364027 | 0.85 | ALPL (0.47) | CRHR1ALPLCNR1CNR2 | |
| SCHEMBL3364228 | 0.84 | CRHR1 (0.46) | KDM4ECRHR1ALPLCNR1CNR2 | |
| Trifluoroacetic Acid SCHEMBL4701370 | 0.84 | CRHR1 (0.46) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656353-B1 | GABANERGIC MODULATORS | HOFFMANN LA ROCHE (CH) | 2010-01-27 | — | — | EP | claimed |