Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 12/20 | 0.61 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365763 | 0.86 | COMT (0.65) | COMTCDK2 | |
| SCHEMBL3363596 | 0.83 | COMT (0.60) | COMTKMT2ACDK2 | |
| SCHEMBL1608934 | 0.82 | COMT (0.83) | COMTKMT2A | |
| SCHEMBL3367675 | 0.77 | COMT (0.46) | COMT | |
| SCHEMBL3362922 | 0.75 | COMT (0.55) | COMTKMT2ACDK2 | |
| SCHEMBL3365925 | 0.74 | COMT (0.59) | COMTKMT2A | |
| SCHEMBL1609327 | 0.73 | COMT (0.69) | COMTKMT2A | |
| SCHEMBL1608186 | 0.72 | COMT (0.73) | COMTCDK2 | |
| SCHEMBL1608920 | 0.68 | COMT (0.49) | COMT | |
| SCHEMBL3365929 | 0.67 | COMT (0.46) | COMTCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910325-B1 | NEW PHARMACEUTICAL COMPOUNDS | ORION CORP (FI) | 2010-10-06 | — | — | EP | claimed |