Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279531 | 0.98 | CA14 (0.41) | CA14CA12CA1CA2CA7 | |
| SCHEMBL10421264 | 0.83 | CA14 (0.44) | CA14CA12CA1CA2CA7 | |
| SCHEMBL5898768 | 0.82 | HTR2C (0.46) | CA14CA12CA1CA2CA7 | |
| SCHEMBL1374441 | 0.81 | CA14 (0.48) | CA14CA12CA1CA2CA7 | |
| SCHEMBL8521398 | 0.81 | CA14 (0.43) | CA14CA12CA1CA2CA7 | |
| SCHEMBL561622 | 0.79 | MAPT (0.47) | CA14CA12CA1CA2CA7 | |
| SCHEMBL13744861 | 0.79 | CA14 (0.41) | CA14CA12CA1CA2CA7 | |
| SCHEMBL6575992 | 0.79 | TYR (0.40) | CA14CA12CA1CA2CA7 | |
| SCHEMBL33604 | 0.78 | PRKCI (0.41) | CA1CA2KDM4EMEN1POLB | |
| SCHEMBL29437148 | 0.78 | PRKCI (0.41) | CA1CA2KDM4EMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5626 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11555017-B2 | Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres | L'OREAL (FR) | 2023-01-17 | — | — | US | claimed |
| US-20200392088-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2020-12-17 | — | — | US | claimed |
| EP-3464247-B1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | OREAL (FR) | 2020-03-11 | — | — | EP | claimed |
| EP-3464247-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'Oréal (FR) | 2019-04-10 | — | — | EP | claimed |
| WO-2017202884-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2017-11-30 | — | — | WO | claimed |
| EP-1870084-B1 | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | claimed |
| EP-0850636-B2 | Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition | OREAL (FR) | 2013-11-20 | — | — | EP | claimed |
| CN-101444460-B | Oxidation dye composition, oxidation dyeing process and use | OU LAIYA | 2013-08-14 | — | — | CN | claimed |
| CN-101766544-B | Composition for the oxidation dyeing of keratin fibers comprising para-aminophenol, dipropylene glycol and at least one additional dye precursor | OREAL | 2013-03-27 | — | — | CN | claimed |
| CN-101091691-B | Keratin fibre dyeing composition containing 2, 3-diamino-6, 7-dihydro-1H, 5H-pyrazolo [1,2-a ] pyrazol-1-one, 6-chloro-2-methyl-5-aminophenol and substituted meta-aminophenol | OREAL | 2012-05-02 | — | — | CN | claimed |
| EP-0733356-A1 | Composition for dyeing keratinous fibres | L'OREAL (FR) | 1996-09-25 | — | — | EP | claimed |
| EP-0728466-A1 | Keratinous fibers oxidation dyeing composition comprising an oxidation base, an indolic coupler and an additional heterocyclic coupler and dyeing process | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| EP-0728463-A1 | Composition for oxidation dyeing of keratinous fibers comprising at least two oxidation bases and an indole coupleur and process for dyeing | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| EP-0722710-A1 | Keratinous fiber oxidation dyeing composition and the dyeing process using this composition | L'OREAL (FR) | 1996-07-24 | — | — | EP | claimed |
| EP-0705598-A1 | Oxidation dye composition for keratinic fibers comprising an association of at least two paraphenylenediamine derivatives, and their use | L'OREAL (FR) | 1996-04-10 | — | — | EP | claimed |
| CN-1109737-A | Composition forthe oxidation dyeingof keratinous fiberes comprising a para-phenylenediamine containinga primary, secondary or tertiary amine function, a meta-phenylenediamine and a para-aminopheno.... | OREAL (FR) | 1995-10-11 | — | — | CN | claimed |
| CN-1110048-A | Novel 3-substituted para-aminophenols and their use for dyeing keratin fibers | OREAL (FR) | 1995-10-11 | — | — | CN | claimed |
| EP-0667143-A1 | Keratinous fiber oxidation dyeing composition containing a paraphenylenediamine, a metaphenylenediamine and a paraaminophenol or a metaaminophenol | L'OREAL (FR) | 1995-08-16 | — | — | EP | claimed |
| EP-0652742-A1 | USE OF 3-SUBSTITUTED PARA-AMINOPHENOLS FOR DYEING KERATINOUS FIBRES AND NOVEL SUBSTITUTED 3-PARA-AMINOPHENOLS. | OREAL (FR) | 1995-05-17 | — | — | EP | claimed |
| WO-1994027564-A1 | USE OF 3-SUBSTITUTED PARA-AMINOPHENOLS FOR DYEING KERATINOUS FIBRES AND NOVEL SUBSTITUTED 3-PARA-AMINOPHENOLS | L'OREAL (FR) | 1994-12-08 | — | — | WO | claimed |