Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 3/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4652273 | 0.98 | ALDH1A1 (0.46) | MAPTALDH1A1POLBHSD17B3CA12 | |
| 3-Aminophenol SCHEMBL21250165 | 0.87 | ALDH1A1 (0.59) | MAPTALDH1A1POLBCA12CA1 | |
| SCHEMBL1425128 | 0.84 | CA12 (0.48) | MAPTHSD17B3CA12CA1CA2 | |
| SCHEMBL4282818 | 0.83 | TYR (0.46) | MAPTHSD17B3CA12CA1CA2 | |
| SCHEMBL10421264 | 0.81 | CA14 (0.44) | MAPTALDH1A1POLBCA12CA1 | |
| SCHEMBL7105504 | 0.81 | ANPEP (0.49) | MAPTALDH1A1HSD17B3JAK2JAK1 | |
| SCHEMBL29531568 | 0.81 | ANPEP (0.49) | MAPTALDH1A1HSD17B3JAK2JAK1 | |
| SCHEMBL5270844 | 0.79 | CYP3A4 (0.39) | ALDH1A1POLBCA12CA1CA2 | |
| SCHEMBL5377496 | 0.79 | TYR (0.61) | MAPTALDH1A1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL33650 | 0.79 | CA14 (0.43) | MAPTALDH1A1POLBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004674-B2 | Substituted p-phenylenediamines as new oxidation dye precursor products of the developer type | HENKEL AG & CO. KGAA (DE) | 2018-06-26 | — | — | US | claimed |
| US-20170165166-A1 | SUBSTITUTED P-PHENYLENEDIAMINES AS NEW OXIDATION DYE PRECURSOR PRODUCTS OF THE DEVELOPER TYPE | HENKEL AG & CO. KGAA (DE) | 2017-06-15 | — | — | US | claimed |
| EP-0920855-B1 | Hair dye compositions containing 3-alkyl-4-aminophenol and 2-substituted 1-naphthol | P & G CLAIROL INC (US) | 2004-01-21 | — | — | EP | claimed |
| CN-1060036-C | Composition forthe oxidation dyeingof keratinous fiberes comprising a para-phenylenediamine containinga primary, secondary or tertiary amine function, a meta-phenylenediamine and a para-aminopheno.... | OREAL (FR) | 2001-01-03 | — | — | CN | claimed |
| US-5984975-A | COLORFAST, WASHFAST HAIR DYES | L'OREAL (FR) | 1999-11-16 | — | — | US | claimed |
| US-5961666-A | Hair dye compositions containing 3-substituted-4-aminophenols and 2-substituted-1-naphthols | NOXELL CORPORATION | 1999-10-05 | — | — | US | claimed |
| EP-0920855-A1 | Hair dye compositions containing 3-alkyl-4-aminophenol and 2-substituted 1-naphthol | Bristol-Myers Squibb Company (US) | 1999-06-09 | — | — | EP | claimed |
| EP-0652742-B1 | USE OF 3-SUBSTITUTED PARA-AMINOPHENOLS FOR DYEING KERATINOUS FIBRES AND NOVEL SUBSTITUTED 3-PARA-AMINOPHENOLS | OREAL (FR) | 1997-08-27 | — | — | EP | claimed |
| EP-0667143-B1 | Keratinous fiber oxidation dyeing composition containing a paraphenylenediamine, a metaphenylenediamine and a paraaminophenol or a metaaminophenol | OREAL (FR) | 1996-10-09 | — | — | EP | claimed |
| CN-1109737-A | Composition forthe oxidation dyeingof keratinous fiberes comprising a para-phenylenediamine containinga primary, secondary or tertiary amine function, a meta-phenylenediamine and a para-aminopheno.... | OREAL (FR) | 1995-10-11 | — | — | CN | claimed |
| CN-1110048-A | Novel 3-substituted para-aminophenols and their use for dyeing keratin fibers | OREAL (FR) | 1995-10-11 | — | — | CN | claimed |
| EP-0667143-A1 | Keratinous fiber oxidation dyeing composition containing a paraphenylenediamine, a metaphenylenediamine and a paraaminophenol or a metaaminophenol | L'OREAL (FR) | 1995-08-16 | — | — | EP | claimed |
| EP-0652742-A1 | USE OF 3-SUBSTITUTED PARA-AMINOPHENOLS FOR DYEING KERATINOUS FIBRES AND NOVEL SUBSTITUTED 3-PARA-AMINOPHENOLS. | OREAL (FR) | 1995-05-17 | — | — | EP | claimed |
| WO-1994027564-A1 | USE OF 3-SUBSTITUTED PARA-AMINOPHENOLS FOR DYEING KERATINOUS FIBRES AND NOVEL SUBSTITUTED 3-PARA-AMINOPHENOLS | L'OREAL (FR) | 1994-12-08 | — | — | WO | claimed |
| EP-0217657-B1 | Low-viscosity epoxy resin, resin composition containing it, and fibre-reinforced composite material containing cured product of the composition | SUMITOMO CHEMICAL CO (JP) | 1994-04-13 | — | — | EP | claimed |
| US-5043083-A | Reacting with primary or secondary amine | EXXON CHEMICAL PATENTS, INC. (US) | 1991-08-27 | — | — | US | claimed |
| EP-0382449-A2 | Method for preparing salts of polyolefinic substituted dicarboxylic acids in oleaginous mixtures of reduced viscosity | EXXON CHEMICAL PATENTS INC. (US) | 1990-08-16 | — | — | EP | claimed |
| EP-4477271-B1 | N-(PHENYL)-5-(HETEROARYL)-1H-PYRAZOL-3-AMINE DERIVATIVES AS TNIK INHIBITORS FOR USE IN THE TREATMENT OF CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2026-05-13 | — | — | EP | disclosed |
| US-4238400-A | USED TO DYE POLYAMIDES BLUE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-12-09 | — | — | US | disclosed |
| US-4007212-A | Novel amide compounds | POLAROID CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10004674-B2 | Substituted p-phenylenediamines as new oxidation dye precursor products of the developer type | KRT18, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-0 | MAPT 2744/4885ALDH1A1 310/4885POLB 645/4885 |
| US-20170165166-A1 | SUBSTITUTED P-PHENYLENEDIAMINES AS NEW OXIDATION DYE PRECURSOR PRODUCTS OF THE DEVELOPER TYPE | KRT18, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-0 | MAPT 2744/4885ALDH1A1 310/4885POLB 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.