Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.63 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368761 | 0.92 | EGLN1 (0.60) | EGLN1ERCC1ERCC4MAPTVNN1 | |
| SCHEMBL3369914 | 0.91 | EGLN1 (0.71) | EGLN1ERCC1ERCC4GAAALDH1A1 | |
| SCHEMBL3371680 | 0.85 | EGLN1 (0.67) | EGLN1ERCC1ERCC4KMT2A | |
| SCHEMBL3368045 | 0.83 | EGLN1 (0.65) | EGLN1GAA | |
| SCHEMBL3367971 | 0.82 | EGLN1 (0.78) | EGLN1 | |
| SCHEMBL3368645 | 0.81 | EGLN1 (0.67) | EGLN1ERCC1ERCC4VNN1 | |
| SCHEMBL3367694 | 0.81 | EGLN1 (0.63) | EGLN1MEN1KMT2AALDH1A1 | |
| SCHEMBL3366469 | 0.81 | EGLN1 (0.72) | EGLN1LMNA | |
| SCHEMBL3371453 | 0.80 | EGLN1 (0.68) | EGLN1MAPTALDH1A1 | |
| SCHEMBL3366533 | 0.79 | EGLN1 (0.57) | EGLN1LMNAVNN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |