Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368045 | 0.86 | EGLN1 (0.65) | EGLN1HPGDTRPV1 | |
| SCHEMBL3367971 | 0.85 | EGLN1 (0.78) | EGLN1 | |
| SCHEMBL3371680 | 0.84 | EGLN1 (0.67) | EGLN1CA1CA2HPGD | |
| SCHEMBL3368307 | 0.83 | EGLN1 (0.58) | EGLN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3369914 | 0.83 | EGLN1 (0.71) | EGLN1KDM4EALDH1A1CA1CA2 | |
| SCHEMBL3367694 | 0.82 | EGLN1 (0.63) | EGLN1ALDH1A1 | |
| SCHEMBL3368761 | 0.81 | EGLN1 (0.60) | EGLN1MAPTIRAK4 | |
| SCHEMBL3370116 | 0.81 | EGLN1 (0.72) | EGLN1 | |
| SCHEMBL3368645 | 0.80 | EGLN1 (0.67) | EGLN1 | |
| SCHEMBL3366064 | 0.80 | EGLN1 (0.63) | EGLN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |