Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 16/20 | 0.67 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3367971 | 0.89 | EGLN1 (0.78) | EGLN1 | |
| SCHEMBL3369914 | 0.88 | EGLN1 (0.71) | EGLN1ERCC1ERCC4 | |
| SCHEMBL3371680 | 0.85 | EGLN1 (0.67) | EGLN1ERCC1ERCC4 | |
| SCHEMBL3366469 | 0.85 | EGLN1 (0.72) | EGLN1 | |
| SCHEMBL3368045 | 0.84 | EGLN1 (0.65) | EGLN1 | |
| SCHEMBL3367694 | 0.81 | EGLN1 (0.63) | EGLN1 | |
| SCHEMBL3366064 | 0.81 | EGLN1 (0.63) | EGLN1VNN1ERCC1ERCC4 | |
| SCHEMBL3371453 | 0.80 | EGLN1 (0.68) | EGLN1 | |
| SCHEMBL3368761 | 0.79 | EGLN1 (0.60) | EGLN1VNN1ERCC1ERCC4 | |
| SCHEMBL3370116 | 0.79 | EGLN1 (0.72) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |