⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138891 | 0.83 | LMNA (0.35) | — | |
| SCHEMBL7617694 | 0.80 | LMNA (0.33) | — | |
| SCHEMBL6266592 | 0.78 | LMNA (0.32) | — | |
| SCHEMBL331509 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL28325076 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL21403444 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL8837687 | 0.74 | — | — | |
| SCHEMBL1819389 | 0.74 | — | — | |
| SCHEMBL12458697 | 0.74 | — | — | |
| SCHEMBL136643 | 0.72 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671227-B2 | Asymmetric bis-silanes and methods for making and their use | CORNING INCORPORATED (US) | 2010-03-02 | — | — | US | disclosed |
| EP-2121710-A1 | ASYMMETRIC BIS-SILANES AND METHODS FOR MAKING AND THEIR USE | CORNING INCORPORATED (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008106132-A9 | ASYMMETRIC BIS-SILANES AND METHODS FOR MAKING AND THEIR USE | CORNING INC (US) | 2009-06-18 | — | — | WO | disclosed |
| WO-2008106132-A1 | ASYMMETRIC BIS-SILANES AND METHODS FOR MAKING AND THEIR USE | CORNING INCORPORATED (US) | 2008-09-04 | — | — | WO | disclosed |
| US-20080207937-A1 | Asymmetric bis-silanes and methods for making and their use | CORNING INCORPORATED | 2008-08-28 | — | — | US | disclosed |