Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362470 | 0.80 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL3362969 | 0.80 | CRHR1 (0.46) | CRHR1CHRM3 | |
| SCHEMBL3364027 | 0.77 | ALPL (0.47) | CRHR1 | |
| SCHEMBL14206617 | 0.77 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL3367449 | 0.74 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3367293 | 0.74 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL3362973 | 0.74 | CRHR1 (0.42) | CRHR1CHRM3 | |
| SCHEMBL3363721 | 0.74 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL4699539 | 0.74 | CRHR1 (0.51) | CRHR1 | |
| Trifluoroacetic Acid SCHEMBL4701873 | 0.74 | CNR1 (0.43) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656353-B1 | GABANERGIC MODULATORS | HOFFMANN LA ROCHE (CH) | 2010-01-27 | — | — | EP | disclosed |
| US-7365211-B2 | Heterocyclic GABAA subtype selective receptor modulators | ROCHE PALO ALTO LLC (US) | 2008-04-29 | — | — | US | disclosed |