Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 6/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846540 | 0.92 | OXTR (0.47) | OXTRAVPR1ACYP2C9MAPTLMNA | |
| SCHEMBL3364267 | 0.85 | OXTR (0.45) | OXTRAVPR1ACYP2C9MAPTLMNA | |
| SCHEMBL3364265 | 0.85 | OXTR (0.45) | OXTRAVPR1ACYP2C9MAPTLMNA | |
| SCHEMBL3366237 | 0.84 | OXTR (0.54) | OXTRAVPR1ACYP2C9MAPTMEN1 | |
| SCHEMBL3366243 | 0.84 | OXTR (0.54) | OXTRAVPR1ACYP2C9MAPTMEN1 | |
| SCHEMBL3366844 | 0.82 | OXTR (0.51) | OXTRAVPR1ACYP2C9MAPTMEN1 | |
| SCHEMBL3369819 | 0.82 | OXTR (0.51) | OXTRAVPR1ACYP2C9MAPTMEN1 | |
| SCHEMBL3366259 | 0.82 | OXTR (0.49) | OXTRAVPR1ACYP2C9MAPTLMNA | |
| SCHEMBL3366261 | 0.82 | OXTR (0.49) | OXTRAVPR1ACYP2C9MAPTLMNA | |
| SCHEMBL3369314 | 0.81 | ALDH1A1 (0.46) | OXTRAVPR1ACYP2C9LMNAPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | claimed |