SCHEMBL336624

SCHEMBL336624

CC(=O)Oc1ccc(OC(C)=O)c(C#N)c1C#N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.46
GAA P10253 1/20 0.46
RAB9A P51151 1/20 0.46
CFD P00746 2/20 0.44
PTGS1 P23219 2/20 0.42
PTGS2 P35354 2/20 0.42
ESR1 P03372 1/20 0.42
ITGB3 P05106 1/20 0.42
ITGA2B P08514 1/20 0.42
HMGB1 P09429 1/20 0.42
HPGD P15428 1/20 0.42
GGT1 P19440 1/20 0.42
BLM P54132 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PIM1 P11309 1/20 0.42
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30453685 1.00 KDM4E (0.46) KDM4ETSHRALDH1A1GAARAB9A
Acetic Acid SCHEMBL336195 0.96 KDM4E (0.47) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL5163600 0.91 PIM1 (0.47) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL15766152 0.87 CFD (0.42) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL15766886 0.87 MAOB (0.40) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL15788597 0.82 ACHE (0.41) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL15788600 0.82 ACHE (0.41) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL11116534 0.81 MAPK1 (0.44) KDM4ETSHRALDH1A1GAARAB9A
SCHEMBL7912820 0.81 NCEH1 (0.47) KDM4ETSHRALDH1A1GAAPTGS1
SCHEMBL10500045 0.80 MRGPRX4 (0.49) KDM4ETSHRALDH1A1GAAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708613-B2 Rapid detection of Zika virus by reverse transcription loop-mediated isothermal amplification The United States of America, as Represened by the Secretary, Department of Health and Human Services (US) 2023-07-25 US claimed
US-20220365074-A1 METHODS AND SYSTEMS FOR DETERMINING VIRUSES SUCH AS CORONAVIRUSES USING pH ANALIZA, INC. (US) 2022-11-17 US claimed
US-10928405-B2 Devices and methods for determining and/or isolating cells such as circulating cancer or fetal cells ANALIZA, INC. (US) 2021-02-23 US claimed
EP-3702783-A1 METHODS FOR DETERMINING CELLS SUCH AS CIRCULATING CANCER OR FETAL CELLS Analiza, Inc. (US) 2020-09-02 EP claimed
US-20200063216-A1 RAPID DETECTION OF ZIKA VIRUS BY REVERSE TRANSCRIPTION LOOP-MEDIATED ISOTHERMAL AMPLIFICATION THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2020-02-27 US claimed
EP-3080341-B1 METHODS FOR DETERMINING AND/OR ISOLATING CELLS SUCH AS CIRCULATING CANCER OR FETAL CELLS ANALIZA INC (US) 2020-02-12 EP claimed
US-20190178901-A1 DEVICES AND METHODS FOR DETERMINING AND/OR ISOLATING CELLS SUCH AS CIRCULATING CANCER OR FETAL CELLS ANALIZA, INC. (US) 2019-06-13 US claimed
WO-2018204175-A1 RAPID DETECTION OF ZIKA VIRUS BY REVERSE TRANSCRIPTION LOOP-MEDIATED ISOTHERMAL AMPLIFICATION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2018-11-08 WO claimed
US-9709556-B2 Devices and methods for determining and/or isolating circulating cancer cells ANALIZA, INC. (US) 2017-07-18 US claimed
EP-3080341-A1 DEVICES AND METHODS FOR DETERMINING AND/OR ISOLATING CELLS SUCH AS CIRCULATING CANCER OR FETAL CELLS Analiza, Inc. (US) 2016-10-19 EP claimed
US-20150160246-A1 DEVICES AND METHODS FOR DETERMINING AND/OR ISOLATING CELLS SUCH AS CIRCULATING CANCER OR FETAL CELLS ANALIZA, INC. (US) 2015-06-11 US claimed
US-20150160198-A1 DEVICES AND METHODS FOR DETERMINING AND/OR ISOLATING CELLS SUCH AS CIRCULATING CANCER OR FETAL CELLS ANALIZA, INC. (US) 2015-06-11 US claimed
EP-2107119-B1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2010-05-12 EP claimed
EP-2107119-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane Millipore Corporation (US) 2009-10-07 EP claimed
US-20090246822-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane EMD MILLIPORE CORPORATION 2009-10-01 US claimed
US-20010012620-A1 Method of reducing cell proliferation by inducing apoptosis in differentially selected cell subpopulations RICH IVAN N (US) 2001-08-09 US claimed
WO-1995000660-A1 METHOD FOR ASSESSING MICROORGANISM VIABILITY CHEMUNEX (FR) 1995-01-05 WO claimed
EP-0057809-B1 METHOD FOR THE DETERMINATION OF THE INTRACELLULAR PH VALUE Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1986-06-18 EP claimed
US-4503148-A Process for determining the pH value in the interior of a cell MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 1985-03-05 US claimed
EP-0057809-A2 Method for the determination of the intracellular pH value Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1982-08-18 EP claimed