SCHEMBL3366440

SCHEMBL3366440

[InH2]c1cnc2ccccc2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.52
KDM4E B2RXH2 4/20 0.48
GPR3 P46089 1/20 0.48
MAPT P10636 2/20 0.48
ALDH1A1 P00352 5/20 0.47
HPGD P15428 4/20 0.47
HSD17B10 Q99714 2/20 0.47
ALOX15 P16050 1/20 0.47
HTT P42858 4/20 0.45
PDGFRB P09619 1/20 0.45
PDGFRA P16234 1/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
BCHE P06276 1/20 0.44
GAA P10253 2/20 0.42
CASP1 P29466 1/20 0.42
MAPK10 P53779 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3076524 0.74 NPC1 (0.63) PDE10AKDM4EGPR3MAPTALDH1A1
SCHEMBL29614829 0.74 NPC1 (0.63) PDE10AKDM4EGPR3MAPTALDH1A1
SCHEMBL29942654 0.74 NPC1 (0.63) PDE10AKDM4EGPR3MAPTALDH1A1
SCHEMBL29966674 0.74 NPC1 (0.63) PDE10AKDM4EGPR3MAPTALDH1A1
SCHEMBL57728 0.72 PDE10A (0.54) PDE10AKDM4EGPR3MAPTALDH1A1
SCHEMBL25427510 0.70 PDE10A (0.52) PDE10AKDM4EGPR3MAPTALDH1A1
SCHEMBL594019 0.70 PDE10A (0.52) PDE10AKDM4EGPR3MAPTALDH1A1
SCHEMBL8400151 0.70 PDE10A (0.52) PDE10AKDM4EGPR3MAPTALDH1A1
SCHEMBL28570 0.70 KDM4E (0.54) PDE10AKDM4EGPR3MAPTALDH1A1
SCHEMBL222284 0.70 SMN1; SMN2 (0.53) PDE10AKDM4EGPR3MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013022610-A1 MESOGENIC STABILIZERS TRANSITIONS OPTICAL, INC. (US) 2013-02-14 WO disclosed
US-7704655-B2 Electrophotographic photoreceptor and electrophotographic apparatus YAMANASHI ELECTRONICS CO., LTD. (JP) 2010-04-27 US disclosed
US-20090004585-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND ELECTROPHOTOGRAPHIC APPARATUS YAMANASHI ELECTRONICS CO., LTD. (JP) 2009-01-01 US disclosed
EP-1980912-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND ELECTROPHOTOGRAPHIC DEVICE Yamanashi Electronics Co. Ltd. (JP) 2008-10-15 EP disclosed
EP-0475676-B1 Electrophotographic member HITACHI CHEMICAL CO LTD (JP) 1996-04-03 EP disclosed
US-5403958-A Fluoroalkoxy-substituted diarylamines as intermediates for charge transfer compounds HITACHI CHEMICAL CO., LTD. (JP) 1995-04-04 US disclosed
US-5352834-A Fluorine-containing N,N,N*,N*-tetraarylbenzidine derivative as charge transport material for electrography HITACHI CHEMICAL COMPANY, LTD. (JP) 1994-10-04 US disclosed
US-5160487-A Tetraarylbenzidine derivative as charge transport compound HITACHI CHEMICAL COMPANY, LTD. (JP) 1992-11-03 US disclosed
EP-0475676-A1 Electrophotographic member HITACHI CHEMICAL CO., LTD. (JP) 1992-03-18 EP disclosed
US-4426327-A PIGMENTS IN ELECTROGRAPHY RICOH CO., LTD. (JP) 1984-01-17 US disclosed
US-4327168-A Electrophotographic element containing disazo pigment charge generating material RICOH CO., LTD. (JP) 1982-04-27 US disclosed
US-4314015-A Electrophotographic sensitive materials containing disazo compounds RICOH CO., LTD. (JP) 1982-02-02 US disclosed
US-4299896-A Electrophotographic sensitive materials containing a disazo pigment RICOH CO., LTD. (JP) 1981-11-10 US disclosed
US-4293628-A Electrophotographic elements containing disazo compounds RICOH CO., LTD. (JP) 1981-10-06 US disclosed
US-4293492-A PHOTOCONDUCTIVITY, ELECTROGRAPHY, PIGMENT RICOH CO., LTD. (JP) 1981-10-06 US disclosed
US-4279981-A Electrophotographic elements containing trisazo compounds RICOH COMPANY, LTD. (JP) 1981-07-21 US disclosed
US-4272598-A STYRYL DYES RICOH CO., LTD. (JP) 1981-06-09 US disclosed
US-4251614-A CARBAZOLE DERIVATIVES RICOH COMPANY, LTD. (JP) 1981-02-17 US disclosed
US-4251613-A LAMINATE OF CONDUCTIVE SUPPORT AND PHOTOSENSITIVE LAYER RICOH COMPANY, LTD. (JP) 1981-02-17 US disclosed
US-4242260-A ELECTROGRAPHY; PHOTOCONDUCTIVITY RICOH COMPANY, LTD. (JP) 1980-12-30 US disclosed