SCHEMBL222284

SCHEMBL222284

Clc1cnc2ccccc2n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
TDP1 Q9NUW8 1/20 0.52
PDE10A Q9Y233 1/20 0.52
ALDH1A1 P00352 4/20 0.50
HTT P42858 5/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
KDM4E B2RXH2 2/20 0.48
GPR3 P46089 1/20 0.48
MAPT P10636 3/20 0.48
HPGD P15428 2/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
PDGFRB P09619 1/20 0.45
PDGFRA P16234 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
BCHE P06276 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30731286 1.00 SMN1; SMN2 (0.53) SMN1; SMN2NPC1RAB9ATDP1PDE10A
Hydrogen Sulfide SCHEMBL28270010 0.98 SMN1; SMN2 (0.52) SMN1; SMN2NPC1RAB9ATDP1PDE10A
Biphenyl SCHEMBL28350717 0.91 NPC1 (0.52) SMN1; SMN2NPC1RAB9ATDP1PDE10A
SCHEMBL16151415 0.88 SMN1; SMN2 (0.44) SMN1; SMN2NPC1RAB9ATDP1PDE10A
Sulfamide SCHEMBL28719576 0.88 HTT (0.50) SMN1; SMN2NPC1RAB9ATDP1PDE10A
SCHEMBL6517140 0.88 NPC1 (0.44) SMN1; SMN2NPC1RAB9ATDP1PDE10A
SCHEMBL28130845 0.88 SMN1; SMN2 (0.44) SMN1; SMN2NPC1RAB9ATDP1PDE10A
SCHEMBL7689829 0.79 ALDH1A1 (0.61) SMN1; SMN2NPC1RAB9ATDP1ALDH1A1
SCHEMBL30754258 0.76 TDP1 (0.48) SMN1; SMN2NPC1RAB9ATDP1PDE10A
SCHEMBL28156588 0.76 ALDH1A1 (0.47) SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1750 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285543-B Sulfonylation method of halogenated quinoline and aryl sulfonyl hydrazine 南京工业大学 2026-05-15 CN claimed
CN-119285543-A Sulfonylation method of halogenated quinoline and aryl sulfonyl hydrazine 南京工业大学 2025-01-10 CN claimed
CN-118996447-A Phosphine-oxide substituted quinoxaline quinazolinone compound, preparation method and application thereof 南阳师范学院 2024-11-22 CN claimed
CN-118388419-A Preparation method of 2-chloro-7-nitroquinoxaline 武威广达科技有限公司 2024-07-26 CN claimed
CN-117110470-A Method for detecting content of impurity 2,3, 6-trichloroquinoxaline in 2, 6-dichloro quinoxaline 山东京博生物科技有限公司 2023-11-24 CN claimed
CN-109970232-B Treatment method and device for waste brine 江苏久吾高科技股份有限公司 2023-06-16 CN claimed
EP-3614141-B1 STABLE URINE INDICATOR WITH LONG-TERM DETECTION AND METHOD FOR ITS PREPARATION AXAGARIUS GMBH & CO KG (DE) 2022-10-05 EP claimed
CN-111141736-B Detection method for identifying 2-chloroquinoxaline 佛山市南海北沙制药有限公司 2022-07-29 CN claimed
CN-114735872-A Method for recycling and reusing sulfanilamide quinoxaline process wastewater 佛山市南海北沙制药有限公司 2022-07-12 CN claimed
CN-114539172-A Method for continuously preparing sulfaquinoxaline without solvent 浙江工业大学 2022-05-27 CN claimed
WO-2003037830-A2 PHOTOACTIVATABLE COMPOSITION AND THE USE OF SAME L'OREAL (FR) 2003-05-08 WO claimed
EP-0167107-B1 PROCESS FOR THE MANUFACTURE OF AQUEOUS, FLUID PREPARATIONS OF REACTIVE DYES WITH A LOW SALT CONTENT HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-08 EP claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
CN-85105802-B Process for preparing low-salt aqueous preparations of fibre-reactive dyes 赫司特公司 1988-07-20 CN claimed
CN-85105802-A The method of the less salt aqueous compositions of preparation fibre-reactive dye 1987-01-28 CN claimed
EP-0058639-B1 2-(4-(6-HALOGEN-QUINOXALINYL-2-OXY)-PHENOXY)-PROPIONIC-ACID ESTERS, PROCESSES FOR THEIR PREPARATION AND THEIR APPLICATION AS HERBICIDES AND PLANT GROWTH REGULATORS CIBA-GEIGY AG (CH) 1985-08-14 EP claimed
EP-0058639-A2 2-(4-(6-Halogen-quinoxalinyl-2-oxy)-phenoxy)-propionic-acid esters, processes for their preparation and their application as herbicides and plant growth regulators CIBA-GEIGY AG (CH) 1982-08-25 EP claimed
EP-0042750-A2 Quinoxalinyloxy ethers as selective weed control agents E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-12-30 EP claimed
US-4119460-A FUSED CARBOCYCLIC RING COMPOUNDS, POLYPHENYL COMPOUNDS NITROGEN-FREE POLYARYLATED COMPOUNDS EASTMAN KODAK COMPANY (US) 1978-10-10 US claimed
US-3989453-A Multicoloring polyester textile materials with acid dyes MARTIN PROCESSING COMPANY, INC. (US) 1976-11-02 US claimed