SCHEMBL3366744

SCHEMBL3366744

CC(C)c1ccc(COC(=O)c2ccc(C(=O)OCc3ccc(C(C)C)cc3)c(C(=O)OCc3ccc(C(C)C)cc3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.49
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 4/20 0.47
TSHR P16473 2/20 0.47
MAPK1 P28482 2/20 0.47
MAPT P10636 5/20 0.45
KDM4E B2RXH2 3/20 0.44
LMNA P02545 2/20 0.44
NPC1 O15118 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27709469 0.89 RXRA (0.53) EGFRRXRARXRBMEN1KMT2A
SCHEMBL23134268 0.82 ROCK1 (0.50) EGFRRXRARXRBMEN1KMT2A
SCHEMBL2580214 0.80 TDP1 (0.66) MEN1KMT2AALDH1A1TSHRMAPK1
SCHEMBL10890743 0.80 EGFR (0.61) EGFRMEN1KMT2AMAPTNPC1
SCHEMBL21376003 0.79 KMT2A (0.69) RXRARXRBMEN1KMT2AALDH1A1
SCHEMBL15614364 0.79 KMT2A (0.69) RXRARXRBMEN1KMT2AALDH1A1
SCHEMBL3679836 0.79 KMT2A (0.47) MEN1KMT2AALDH1A1TSHRMAPK1
SCHEMBL4734206 0.78 TYR (0.56) EGFRRXRARXRBMEN1KMT2A
SCHEMBL8425259 0.77 KMT2A (0.49) MEN1KMT2AALDH1A1TSHRMAPK1
SCHEMBL22621436 0.77 MEN1 (0.50) RXRARXRBMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7738819-B2 Image forming method and apparatus, and developing device and process cartridge therefor RICOH COMPANY LIMITED (JP) 2010-06-15 US disclosed
US-20060245794-A1 Image forming method and apparatus, and developing device and process cartridge therefor RICOH COMPANY LIMITED (JP) 2006-11-02 US disclosed
US-6818370-B2 A COLORANT AND A BINDER RESIN COMPOSED OF TWO DIFFERENT RESINS (A) AND (B), WHEREIN (A) IS FREE OF TETRAHYDROFURAN INSOLUBLES, IS SELECTED FROM POLYESTER AND POLYOL RESINS AND (B) CONTAINS PROPOXYLATED BISPHENOL A AS POLYOL RICOH COMPANY, LTD. (JP) 2004-11-16 US disclosed
US-20030162115-A1 Toner for developing electrostatic latent image, toner cartridge containing the toner and image forming apparatus RICOH COMPANY, LTD. (JP) 2003-08-28 US disclosed