SCHEMBL2580214

SCHEMBL2580214

O=C(OCc1ccccc1)c1ccc(C(=O)OCc2ccccc2)c(C(=O)OCc2ccccc2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.66
KMT2A Q03164 4/20 0.66
SLC6A2 P23975 1/20 0.66
SLC6A3 Q01959 1/20 0.66
ALDH1A1 P00352 7/20 0.65
LMNA P02545 3/20 0.65
RAB9A P51151 5/20 0.60
MAPT P10636 3/20 0.60
NPC1 O15118 3/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
HPGD P15428 1/20 0.56
L3MBTL1 Q9Y468 3/20 0.55
CYP3A4 P08684 2/20 0.55
TSHR P16473 1/20 0.55
MAPK1 P28482 1/20 0.55
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
MEN1 O00255 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16016782 0.92 ALDH1A1 (0.63) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL4941110 0.92 ALDH1A1 (0.68) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL5337167 0.91 TDP1 (0.58) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL5834916 0.89 ALDH1A1 (0.68) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL4885685 0.88 ALDH1A1 (0.78) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL4893027 0.88 ALDH1A1 (0.78) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL4885717 0.88 ALDH1A1 (0.78) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL4894199 0.88 ALDH1A1 (0.78) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL5834481 0.88 ALDH1A1 (0.62) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL5333023 0.87 TDP1 (0.69) TDP1KMT2ASLC6A2SLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080306190-A1 Composition of matter based on alkyl benzyl esters LANXESS DEUTSCHLAND GMBH (DE) 2008-12-11 US claimed
US-20080004387-A1 Alkyl benzyl esters of polycarboxylic acids LANXESS DEUTSCHLAND GMBH (DE) 2008-01-03 US claimed
JP-8020668-A None JP disclosed
CN-113728054-B Alkali solution resistance improving method for thermoplastic resin 宝理塑料株式会社 2023-07-11 CN disclosed
US-20220195179-A1 METHOD FOR IMPROVING ALKALINE SOLUTION RESISTANCE OF THERMOPLASTIC RESINS POLYPLASTICS CO., LTD. (JP) 2022-06-23 US disclosed
CN-113728054-A Method for improving alkali-resistant solution property of thermoplastic resin 宝理塑料株式会社 2021-11-30 CN disclosed
CN-107428857-B Thermally expandable microspheres and use thereof 松本油脂制药株式会社 2020-05-26 CN disclosed
US-20180056267-A1 HEAT-EXPANDABLE MICROSPHERES AND APPLICATION THEREOF MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) 2018-03-01 US disclosed
US-8900783-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-12-02 US disclosed
US-8900783-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-12-02 US disclosed
US-20140255835-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-09-11 US disclosed
US-20030144447-A1 Novel polyvalent carboxylic acid ester and their use in plastic lens compositions SHOW A DENKO K.K. (JP) 2003-07-31 US disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
WO-2002079140-A1 NOVEL POLYVALENT CARBOXYLIC ACID ESTERS AND THEIR USE IN PLASTIC LENS COMPOSITIONS SHOWA DENKO K. K. (JP) 2002-10-10 WO disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed
EP-0699543-B1 Printing paper SONY CORP (JP) 1999-12-01 EP disclosed
US-5635441-A SHEET SUBSTRATE HAVING DYE RECEIVING LAYER OF CROSSLINKED COATING OBTAINED BY CURING MIXTURE OF BUTYRAL RESIN, VINYLPHENOLIC RESIN, POLYISOCYANATE; STORAGE STABLE IMAGES SONY CORPORATION (JP) 1997-06-03 US disclosed
EP-0699543-A1 Printing paper SONY CORPORATION (JP) 1996-03-06 EP disclosed
JP-H0820668-A THERMOPLASTIC RESIN COMPOSITION, ADHESIVE AND ADHESIVE BASE MATERIAL DAINIPPON INK & CHEM INC 1996-01-23 JP disclosed
EP-0358484-A2 Process for preparation of 1-benzylimidazole compound, and its compound SHIKOKU CHEMICALS CORPORATION (JP) 1990-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144447-A1 Novel polyvalent carboxylic acid ester and their use in plastic lens compositions VCL, VIM, CRYAA TDP1 3601/4885KMT2A 334/4885SLC6A2 4864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.