Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | S100A4 | P26447 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868587 | 0.85 | KMT2A (0.73) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL14567015 | 0.79 | POLB (0.65) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL23457291 | 0.78 | KMT2A (0.64) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL9393278 | 0.76 | MEN1 (0.59) | KMT2AMEN1POLBMAPTLMNA | |
| SCHEMBL2130350 | 0.71 | KMT2A (0.55) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL6081753 | 0.71 | MEN1 (0.55) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL15245116 | 0.71 | MEN1 (0.55) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL5808584 | 0.71 | MAPT (0.56) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL677629 | 0.71 | MEN1 (0.55) | KMT2AMEN1POLBS100A4MAPT | |
| SCHEMBL10344203 | 0.71 | MEN1 (0.55) | KMT2AMEN1POLBS100A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9717699-B2 | Sterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides | ADHEZION BIOMEDICAL, LLC (US) | 2017-08-01 | — | — | US | claimed |
| US-20160331700-A1 | Sterilized Compositions of Cyanoacrylate Monomers and Naphthoquinone 2,3-Oxides | H.B. FULLER MEDICAL ADHESIVE TECHNOLOGIES, LLC. | 2016-11-17 | — | — | US | claimed |
| US-20150283290-A1 | STERILIZED COMPOSITIONS OF CYANOACRYLATE MONOMERS AND NAPHTHOQUINONE 2,3-OXIDES | ADHEZION BIOMEDICAL, LLC (US) | 2015-10-08 | — | — | US | claimed |
| WO-2002068056-A2 | COMBINATION COMPRISING A 1,4-DIOXONAPHATHALENE COMPOUND AND RIBENOSIDE | KS BIOMEDIX HOLDINGS PLC (GB) | 2002-09-06 | — | — | WO | claimed |
| JP-3251582-B2 | — | — | 2002-01-28 | — | — | JP | claimed |
| EP-0570414-B1 | NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION | KS BIOMEDIX LTD (GB) | 2000-07-05 | — | — | EP | claimed |
| US-5763479-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIS AGENTS | KS BIOMEDIX LTD. (GB) | 1998-06-09 | — | — | US | claimed |
| EP-0570414-A1 | NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION | KS BIOMEDIX LTD. (GB) | 1993-11-24 | — | — | EP | claimed |
| WO-1992013532-A2 | NAPHTHOQUINONE DERIVATIVES FOR THE TREATMENT OF CHRONIC INFLAMMATION | CHAYEN JOSEPH (GB) | 1992-08-20 | — | — | WO | claimed |
| EP-0226842-A2 | Substituted 1,4-naphthalenediones, processes for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1987-07-01 | — | — | EP | claimed |
| EP-0149818-A2 | 1,4-Naphthoquinone derivatives, process for their preparation and their use as medicines | Troponwerke GmbH & Co. KG (DE) | 1985-07-31 | — | — | EP | claimed |
| JP-4159271-A | — | — | None | — | — | JP | disclosed |
| JP-53092746-A | — | — | None | — | — | JP | disclosed |
| JP-3163072-A | — | — | None | — | — | JP | disclosed |
| JP-59005175-A | — | — | None | — | — | JP | disclosed |
| JP-S5392746-A | PREPARATION OF 2-HYDROXY-1, 4-NAPHTHOQUINONE | KAWASAKI KASEI CHEM LTD | 1978-08-15 | — | — | JP | disclosed |
| JP-S5346946-A | PREPARATION OF 2-HYDROXY-3-HALOGENO-1,4-NAPHTHOQUINONE COPPER SALT | KAWASAKI KASEI CHEM LTD | 1978-04-27 | — | — | JP | disclosed |
| JP-S5315352-A | PREPARATION OF 2,2'-DIHYDROXY-3,3'-BI-1,4-NAPHTHOQUINOLYL | KAWASAKI KASEI CHEM LTD | 1978-02-13 | — | — | JP | disclosed |
| JP-S5315350-A | PREPARATION OF 2-HYDROXY-1,4-NAPHTHOQUINONE | KAWASAKI KASEI CHEM LTD | 1978-02-13 | — | — | JP | disclosed |
| JP-S5278859-A | PREPARATION OF 2,3-EPOXY-2,3-DIHYDRO-1,4-NAPHTHOQUINONE | KAWASAKI KASEI CHEM LTD | 1977-07-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160331700-A1 | Sterilized Compositions of Cyanoacrylate Monomers and Naphthoquinone 2,3-Oxides | PROC, CCNK, MMS19 | KMT2A 3061/4885MEN1 699/4885POLB 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.