Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 8/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362365 | 0.90 | HTR6 (0.42) | MEN1KMT2AHTR6FLT1FLT4 | |
| SCHEMBL3361493 | 0.90 | PPARG (0.42) | HTR6FLT1FLT4KDRPPARG | |
| SCHEMBL3362896 | 0.90 | HTR6 (0.44) | HTR6PPARGCA2CA9CYP3A4 | |
| SCHEMBL3366631 | 0.89 | FLT1 (0.43) | MEN1KMT2AHTR6FLT1FLT4 | |
| SCHEMBL3363097 | 0.86 | HTR6 (0.42) | MEN1KMT2AHTR6FLT1FLT4 | |
| SCHEMBL3132165 | 0.83 | AKR1C3 (0.50) | MEN1KMT2AHTR6FLT1FLT4 | |
| SCHEMBL3137579 | 0.80 | FLT1 (0.46) | MEN1KMT2AHTR6FLT1FLT4 | |
| SCHEMBL3133901 | 0.78 | PLK1 (0.55) | MEN1KMT2AHTR6FLT1FLT4 | |
| SCHEMBL3145976 | 0.78 | HDAC1 (0.48) | MEN1KMT2AHTR6FLT1FLT4 | |
| SCHEMBL3141520 | 0.78 | FLT1 (0.47) | MEN1KMT2AHTR6FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118060-B1 | 1-BENZENESULFONYL-1H-INDOLE DERIVATIVES AS INHIBITORS OF CCR9 ACTIVITY | NOVARTIS AG (CH) | 2010-10-06 | — | — | EP | claimed |