Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 2/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136904 | 0.96 | NPC1 (0.77) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL4611341 | 0.95 | NPC1 (0.75) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL9135757 | 0.95 | NPC1 (0.75) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL5350428 | 0.92 | NPC1 (0.89) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL1148371 | 0.92 | NPC1 (0.89) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL5350433 | 0.92 | NPC1 (0.89) | NPC1RAB9APOLBALDH1A1LMNA | |
| Bicarbonate SCHEMBL11475731 | 0.89 | NPC1 (0.83) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL16861595 | 0.84 | NPC1 (0.71) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL4675008 | 0.84 | NPC1 (0.71) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL230405 | 0.84 | NPC1 (0.71) | NPC1RAB9APOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401388-B1 | FRAGRANCE AND FLAVOUR COMPOSITIONS | GIVAUDAN SA (CH) | 2010-06-16 | — | — | EP | disclosed |
| US-7704942-B2 | Fragrance and flavour compositions | GIVAUDAN SA (CH) | 2010-04-27 | — | — | US | disclosed |
| US-20050042255-A1 | Fragrance and flavour compositions | GIVAUDAN SA (CH) | 2005-02-24 | — | — | US | disclosed |
| EP-1401388-A2 | FRAGRANCE AND FLAVOUR COMPOSITIONS | Givaudan SA (CH) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003002084-A2 | FRAGRANCE AND FLAVOUR COMPOSITIONS | GIVAUDAN SA (CH) | 2003-01-09 | — | — | WO | disclosed |
| EP-1269982-A1 | Fragrance and flavour compositions | Givaudan SA (CH) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050042255-A1 | Fragrance and flavour compositions | C5, FAAH2, TRPA1 | NPC1 2738/4885RAB9A 4044/4885POLB 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.