Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565885 | 0.77 | GLA (0.36) | EPHX1SHBG | |
| SCHEMBL21695690 | 0.77 | EPHX1 (0.34) | EPHX1SHBG | |
| SCHEMBL135096 | 0.73 | SHBG (0.44) | EPHX1SHBG | |
| SCHEMBL6565919 | 0.72 | HIF1A (0.35) | EPHX1SHBG | |
| SCHEMBL10729418 | 0.71 | EPHX1 (0.42) | EPHX1SHBG | |
| SCHEMBL135097 | 0.71 | SHBG (0.48) | EPHX1SHBG | |
| SCHEMBL27859422 | 0.71 | SHBG (0.48) | EPHX1SHBG | |
| SCHEMBL8009642 | 0.71 | SHBG (0.37) | EPHX1SHBG | |
| SCHEMBL5545142 | 0.71 | SHBG (0.37) | EPHX1SHBG | |
| SCHEMBL25568097 | 0.71 | SHBG (0.37) | EPHX1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776349-B1 | 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-06 | — | — | EP | disclosed |