Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542682 | 0.98 | SHBG (0.41) | SHBGEPHX1TP53 | |
| SCHEMBL5541917 | 0.98 | SHBG (0.41) | SHBGEPHX1TP53 | |
| SCHEMBL20600327 | 0.98 | SHBG (0.41) | SHBGEPHX1TP53 | |
| SCHEMBL5542043 | 0.98 | SHBG (0.41) | SHBGEPHX1TP53 | |
| SCHEMBL11257495 | 0.98 | SHBG (0.41) | SHBGEPHX1TP53 | |
| SCHEMBL5542322 | 0.95 | — | — | |
| SCHEMBL5544181 | 0.90 | — | — | |
| SCHEMBL7093118 | 0.87 | SHBG (0.32) | SHBGEPHX1 | |
| SCHEMBL58339 | 0.86 | SHBG (0.34) | SHBGEPHX1 | |
| SCHEMBL6741115 | 0.84 | SHBG (0.38) | SHBGEPHX1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-20040043903-A1 | Herbicides; applying to plants | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-04 | — | — | US | disclosed |
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |
| US-20030216257-A1 | 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-20 | — | — | US | disclosed |
| US-6482774-B1 | Substituted (4-brompyrazole-3-yl) benzazoles | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-19 | — | — | US | disclosed |
| EP-1214092-A2 | METHOD OF POTENTIATING CHEMOTHERAPY AND TREATING SOLID TUMORS | Wyeth (US) | 2002-06-19 | — | — | EP | disclosed |
| US-6054412-A | AGRICULTURE, HORTICULTURE | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-25 | — | — | US | disclosed |
| CN-1244865-A | Substituted pyrazole-3-yl benzazoles | BASF AK (DE) | 2000-02-16 | — | — | CN | disclosed |
| US-5658945-A | ANTICANCER AGENT; AIDS THERAPY; CONTROLLING INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1997-08-19 | — | — | US | disclosed |
| US-5633280-A | ACCELERATED RECOVERY FROM CHEMOTHERAPY, RADIATION TREATMENT, BONE MARROW TRANSPLANTATION, INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| US-5616612-A | THERAPY FOR CANCER, AIDS, ANEMIA, INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1997-04-01 | — | — | US | disclosed |
| US-5602275-A | MAY BE USED TO ACCELERATE RECOVERY FROM NEUTROPENIA ACCOMPANYING RADIO- OR CHEMOTHERAPY, BONE MARROW TRANSPLANTATION OR INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0652228-B1 | Urethanes and ureas that induce cytokine production | AMERICAN CYANAMID CO (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5545662-A | USED TO ACCELERATE RECOVERY FROM NEUTROPENIA ACCOMPANYING RADIO OR CHEMOTHERAPY, BONE MARROW TRANSPLANTATION, OR INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0652228-A1 | Urethanes and ureas that induce cytokine production | AMERICAN CYANAMID COMPANY (US) | 1995-05-10 | — | — | EP | disclosed |
| US-5312831-A | Immunology, anticarcinogenic agents and AIDS treatment | AMERICAN CYANAMID COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | DDT, HAX1, SULT1E1 | SHBG 3782/4885EPHX1 1368/4885TP53 2824/4885 |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | SHBG 3836/4885EPHX1 4071/4885TP53 4494/4885 |
| US-20040043903-A1 | Herbicides; applying to plants | DDT, DRD1, DRD4 | SHBG 4130/4885EPHX1 805/4885TP53 3184/4885 |
| US-20030216257-A1 | 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides | CYP1B1, DDT, CYP1A1 | SHBG 4562/4885EPHX1 372/4885TP53 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.