Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | OXTR | P30559 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366054 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KDM4ELMNAOXTR | |
| SCHEMBL3366051 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KDM4ELMNAOXTR | |
| SCHEMBL3366955 | 0.95 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1KDM4ELMNAOXTR | |
| SCHEMBL3366952 | 0.95 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1KDM4ELMNAOXTR | |
| SCHEMBL3396501 | 0.95 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1KDM4ELMNAOXTR | |
| SCHEMBL3369910 | 0.92 | MEN1 (0.56) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL3369917 | 0.92 | MEN1 (0.56) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL3366411 | 0.91 | MEN1 (0.51) | SMN1; SMN2ALDH1A1KDM4ELMNAOXTR | |
| SCHEMBL5641723 | 0.91 | MEN1 (0.51) | SMN1; SMN2ALDH1A1KDM4ELMNAOXTR | |
| SCHEMBL3364599 | 0.91 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1KDM4ELMNAOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-20040072816-A1 | Pharmaceutically active sulfanilide derivatives | MERCK SERONO SA (CH) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072816-A1 | Pharmaceutically active sulfanilide derivatives | OXTR, AVPR2, OPRL1 | SMN1; SMN2 1062/4885ALDH1A1 2629/4885KDM4E 4652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.