Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77070 | 1.00 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL27291145 | 1.00 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL16363070 | 1.00 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL10038033 | 1.00 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| Hydrochloric Acid SCHEMBL28223198 | 0.97 | DPP4 (0.65) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL10506371 | 0.83 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL522687 | 0.83 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL7286165 | 0.83 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL1980156 | 0.83 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL851654 | 0.82 | DPP4 (1.00) | DPP4ADRA2AADRA2CLMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002577-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | 富士フイルム株式会社 (JP) | 2012-01-05 | — | — | WO | disclosed |