Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291145 | 1.00 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL16363070 | 1.00 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL3367415 | 1.00 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL10038033 | 1.00 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| Hydrochloric Acid SCHEMBL28223198 | 0.97 | DPP4 (0.65) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL10506371 | 0.83 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL522687 | 0.83 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL7286165 | 0.83 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL1980156 | 0.83 | DPP4 (0.68) | DPP4ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL851654 | 0.82 | DPP4 (1.00) | DPP4ADRA2AADRA2CLMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3064530-B1 | XYLYLENE DIAMINE COMPOSITION, AND METHOD FOR PRODUCING POLYAMIDE RESIN | MITSUBISHI GAS CHEMICAL CO (JP) | 2018-09-05 | — | — | EP | claimed |
| US-9637594-B2 | Xylylene diamine composition, and method for producing polyamide resin | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-05-02 | — | — | US | claimed |
| US-20160304671-A1 | XYLYLENE DIAMINE COMPOSITION, AND METHOD FOR PRODUCING POLYAMIDE RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-10-20 | — | — | US | claimed |
| EP-3064530-A1 | XYLYLENE DIAMINE COMPOSITION, AND METHOD FOR PRODUCING POLYAMIDE RESIN | Mitsubishi Gas Chemical Company, Inc. (JP) | 2016-09-07 | — | — | EP | claimed |
| EP-3551626-B1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2023-10-25 | — | — | EP | disclosed |
| EP-3239137-B1 | (5R)-4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AS WELL AS 1-(2-CHLOROACETYL)-4-PIPERIDINE-CARBONITRILE AND -CARBOXAMIDE DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF E.G. 4-[4-[(5R)-4,5-DIHYDRO-ISOXAZOL-3-YL]-THIAZOL-2-YL]-PIPERIDINE DERIVATIVES AS FUNGICIDES FOR CROP PROTECTION | DU PONT (US) | 2019-02-13 | — | — | EP | disclosed |
| EP-3064530-B1 | XYLYLENE DIAMINE COMPOSITION, AND METHOD FOR PRODUCING POLYAMIDE RESIN | MITSUBISHI GAS CHEMICAL CO (JP) | 2018-09-05 | — | — | EP | disclosed |
| CN-104053661-B | The thienopyrimidines inhibitor of atypical protein kinase C | 癌症研究技术有限公司 | 2018-06-19 | — | — | CN | disclosed |
| US-9920030-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-03-20 | — | — | US | disclosed |
| CN-107698748-A | A kind of dynamic aggregation thing of hybrid cross-linked network and its application | 翁秋梅 | 2018-02-16 | — | — | CN | disclosed |
| EP-3239145-A1 | 1-[2-[3,5-SUBSTITUTED-1H-PYRAZOL-1-YL]ACETYL]-4-PIPERIDINE-CARBONITRILE AND -CARBOTHIAMIDE DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF FUNGICIDES FOR CROP PROTECTION | E. I. du Pont de Nemours and Company (US) | 2017-11-01 | — | — | EP | disclosed |
| EP-3239137-A1 | (5R)-4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AS WELL AS 1-(2-CHLOROACETYL)-4-PIPERIDINE-CARBONITRILE AND -CARBOXAMIDE DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF E.G. 4-[4-[(5R)-4,5-DIHYDRO-ISOXAZOL-3-YL]-THIAZOL-2-YL]-PIPERIDINE DERIVATIVES AS FUNGICIDES FOR CROP PROTECTION | E. I. du Pont de Nemours and Company (US) | 2017-11-01 | — | — | EP | disclosed |
| US-20020037907-A1 | Substituted 2- (S) -hydroxy-3- (piperidin-4-yl-methylamino) -propyl ethers and substituted 2-aryl-2- (R) - hydroxy-1- (piperidin-4-yl-methyl) -ethylamine beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-03-28 | — | — | US | disclosed |
| WO-2002006255-A2 | HYDROXY-(PIPERIDIN-4-YL-METHYLAMINO)-ALKYL BETA-3 ADRENERGIC RECEPTOR ANTAGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |
| WO-2001046157-A1 | BENZO[A]PHENAZIN-11-CARBOXAMIDE DERIVATIVES AND THEIR USE AS JOINT INHIBITORS OF TOPOMERASE I AND II | XENOVA LIMITED (GB) | 2001-06-28 | — | — | WO | disclosed |
| US-4289885-A | 3-[2-(Dimethylamino)-2-phenylethyl]N-[phenylamino)carbonyl]sydnone imine, a new central nervous system stimulant | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| US-4284775-A | 1,4-Diazabicyclooctane di-N,N'-quaternized compounds | THE UPJOHN COMPANY (US) | 1981-08-18 | — | — | US | disclosed |
| US-4216322-A | Process for making triethylene diamines | THE UPJOHN COMPANY (US) | 1980-08-05 | — | — | US | disclosed |
| US-4193905-A | Curable epoxide resin mixtures containing diaminopropanes | CIBA-GEIGY CORPORATION (US) | 1980-03-18 | — | — | US | disclosed |
| US-4143188-A | GLYCIDYL COMPOUND CONTAINING AN N-HETEROCYCLIC GROUP HARDENED WITH AN AMINE | CIBA-GEIGY CORPORATION (US) | 1979-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037907-A1 | Substituted 2- (S) -hydroxy-3- (piperidin-4-yl-methylamino) -propyl ethers and substituted 2-aryl-2- (R) - hydroxy-1- (piperidin-4-yl-methyl) -ethylamine beta-3 adrenergic receptor agonists | GPR119, ADRB1, ADRB2 | DPP4 404/4885ADRA2A 14/4885ADRA2C 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.