Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363869 | 0.74 | FDPS (0.44) | HIF1ASMN1; SMN2FDPSCYP2C9CYP2C19 | |
| SCHEMBL7271492 | 0.71 | SMN1; SMN2 (0.42) | HIF1ASMN1; SMN2FDPSCYP2C9CYP2C19 | |
| SCHEMBL3363867 | 0.71 | FDPS (0.46) | HIF1ASMN1; SMN2FDPSCYP2C9CYP2C19 | |
| SCHEMBL10476772 | 0.71 | CYP1A2 (0.61) | HIF1ASMN1; SMN2FDPSCYP2C9CYP2C19 | |
| SCHEMBL28607388 | 0.71 | CYP1A2 (0.61) | HIF1ASMN1; SMN2FDPSCYP2C9CYP2C19 | |
| SCHEMBL1421007 | 0.71 | CYP1A2 (0.61) | HIF1ASMN1; SMN2FDPSCYP2C9CYP2C19 | |
| SCHEMBL28644127 | 0.70 | CYP1A2 (0.54) | HIF1ASMN1; SMN2FDPSCYP2C9CYP2C19 | |
| Diphenylmethane SCHEMBL1537806 | 0.69 | CALM1 (0.67) | CES1CES2AKR1B1LMNATSHR | |
| Ammonia Solution, Strong SCHEMBL29962813 | 0.69 | CYP1A2 (0.58) | HIF1ASMN1; SMN2FDPSCYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL4608399 | 0.69 | CYP1A2 (0.58) | HIF1ASMN1; SMN2FDPSCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056795-A1 | NOVEL SYNTHETIC DINUCLEOSIDE POLYPHOSPHATE ANALOGS AND THEIR USE AS NEW THERAPEUTIC AND/OR DIAGNOSTIC MODALITIES | ZATA PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |