Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727986 | 0.92 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDCCR5TDP1 | |
| SCHEMBL9208976 | 0.92 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDCCR5TDP1 | |
| SCHEMBL337168 | 0.92 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDCCR5TDP1 | |
| SCHEMBL336792 | 0.92 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDCCR5TDP1 | |
| SCHEMBL9205224 | 0.92 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDCCR5TDP1 | |
| SCHEMBL9196975 | 0.86 | RAB9A (0.45) | ALDH1A1MAPTHPGDTDP1LMNA | |
| SCHEMBL9205873 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDTDP1LMNA | |
| SCHEMBL9734477 | 0.84 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDCCR5TDP1 | |
| SCHEMBL9687135 | 0.83 | POLB (0.45) | ALDH1A1MAPTHPGDCCR5TDP1 | |
| SCHEMBL28705506 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDCCR5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411636-B1 | Piperidylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5153188-A | Thienamycin antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0411636-A2 | Piperidylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |