Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370278 | 0.86 | TRPM8 (0.58) | SMN1; SMN2RAB9AKDM4EGAANPC1 | |
| SCHEMBL3371761 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2RAB9AKDM4EGAANPC1 | |
| SCHEMBL3371496 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9AKDM4EGAANPC1 | |
| SCHEMBL289112 | 0.83 | SMN1; SMN2 (0.93) | SMN1; SMN2RAB9AKDM4EGAANPC1 | |
| SCHEMBL3371972 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9AKDM4EGAANPC1 | |
| SCHEMBL3368992 | 0.81 | KDM4E (0.63) | SMN1; SMN2RAB9AKDM4EGAANPC1 | |
| SCHEMBL3371793 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9AKDM4EGAANPC1 | |
| SCHEMBL1327631 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9AKDM4EGAANPC1 | |
| SCHEMBL289852 | 0.78 | SMN1; SMN2 (0.73) | SMN1; SMN2RAB9AKDM4EGAANPC1 | |
| SCHEMBL289371 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9AKDM4EGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |