Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371749 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL3368992 | 0.83 | KDM4E (0.63) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL3367686 | 0.83 | CDC7 (0.55) | SMN1; SMN2KDM4ERAB9ANPC1KMT2A | |
| SCHEMBL3371793 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL3367949 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL3371761 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL3371496 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL8339818 | 0.78 | RAB9A (0.77) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL11051000 | 0.73 | KDM4E (0.46) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL2011167 | 0.73 | RAB9A (0.79) | SMN1; SMN2KDM4ERAB9AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |