Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.42 |
| ▸ | ITGAV | P06756 | 12/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5972640 | 0.92 | VDR (0.48) | VDRITGB3ITGAVITGA2BCACNA1G | |
| SCHEMBL5972894 | 0.91 | VDR (0.49) | VDRITGB3ITGAVITGA2B | |
| SCHEMBL5972711 | 0.87 | VDR (0.46) | VDRITGB3ITGAVITGA2B | |
| SCHEMBL337308 | 0.86 | VDR (0.48) | VDRITGB3ITGAVITGA2B | |
| SCHEMBL337320 | 0.83 | ITGB3 (0.62) | ITGB3ITGAVITGA2B | |
| SCHEMBL5972558 | 0.81 | ITGB3 (0.48) | VDRITGB3ITGAVITGA2B | |
| SCHEMBL5973364 | 0.79 | ITGB3 (0.49) | VDRITGB3ITGAVITGA2B | |
| SCHEMBL7668371 | 0.77 | ITGB3 (0.58) | ITGB3ITGAVITGA2B | |
| SCHEMBL337310 | 0.77 | ITGB3 (0.48) | ITGB3ITGAVITGA2B | |
| SCHEMBL5155928 | 0.74 | ITGB3 (0.57) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443963-B1 | ANTIBODY TARGETING COMPOUNDS | SCRIPPS RESEARCH INST (US) | 2014-05-21 | — | — | EP | disclosed |
| US-8252902-B2 | Complexing antigen, antibodies; immunoassay | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2428226-A1 | Antibody targeting compounds | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-03-14 | — | — | EP | disclosed |