Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368515 | 0.83 | EGLN1 (0.65) | EGLN1MAPTMEN1KMT2AMCOLN3 | |
| SCHEMBL3371512 | 0.75 | TSHR (0.39) | MAPTMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL3369838 | 0.70 | EGLN1 (0.53) | EGLN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3369100 | 0.69 | EGLN1 (0.66) | EGLN1KMT2A | |
| SCHEMBL12469055 | 0.68 | ALDH1A1 (0.51) | MAPTMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL3368397 | 0.68 | EGLN1 (0.71) | EGLN1 | |
| SCHEMBL3366073 | 0.68 | EGLN1 (0.58) | EGLN1SMN1; SMN2 | |
| SCHEMBL28807585 | 0.68 | TSHR (0.49) | MAPTMEN1KMT2ATSHRHSD17B10 | |
| SCHEMBL3371408 | 0.63 | LMNA (0.38) | MAPTKMT2ATSHRHSD17B10ALDH1A1 | |
| SCHEMBL17472745 | 0.62 | CTNNB1 (0.47) | MEN1KMT2ATSHRPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |