Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369704 | 0.95 | F10 (0.54) | F10F2CCNKCDK12 | |
| SCHEMBL3372878 | 0.85 | F10 (0.56) | F10F2 | |
| SCHEMBL3372965 | 0.85 | F10 (0.66) | F10F2 | |
| SCHEMBL3368811 | 0.84 | F10 (0.51) | F10F2 | |
| SCHEMBL6017050 | 0.83 | F10 (0.49) | F10F2CCNKCDK12ACSS2 | |
| SCHEMBL1379542 | 0.83 | F10 (0.60) | F10F2 | |
| SCHEMBL3369753 | 0.82 | F10 (0.54) | F10F2 | |
| SCHEMBL1653789 | 0.82 | F10 (0.73) | F10F2 | |
| SCHEMBL3370345 | 0.78 | F10 (0.54) | F10F2 | |
| SCHEMBL1379145 | 0.78 | F10 (0.63) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-B1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-07-21 | — | — | EP | claimed |