Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369990 | 0.90 | ACSS2 (0.45) | F10F2ACSS2CCNKCDK12 | |
| SCHEMBL3373231 | 0.83 | F10 (0.42) | F10F2ACSS2CCNKCDK12 | |
| SCHEMBL1379542 | 0.83 | F10 (0.60) | F10F2 | |
| SCHEMBL6016992 | 0.83 | F10 (0.46) | F10F2PADI4CCNT1CDK9 | |
| SCHEMBL3368978 | 0.83 | F10 (0.54) | F10F2ACSS2CCNKCDK12 | |
| SCHEMBL1377971 | 0.81 | F10 (0.65) | F10F2 | |
| SCHEMBL1653789 | 0.78 | F10 (0.73) | F10F2 | |
| SCHEMBL3798321 | 0.78 | F10 (0.48) | F10ALDH1A1 | |
| SCHEMBL3369704 | 0.77 | F10 (0.54) | F10F2CCNKCDK12 | |
| SCHEMBL1379145 | 0.77 | F10 (0.63) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |