Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6619629 | 1.00 | DPP8 (0.38) | DPP8DPP7DPP9DPP4ACE | |
| SCHEMBL5551891 | 0.95 | DPP8 (0.36) | DPP8DPP7DPP9DPP4ACE | |
| SCHEMBL3370863 | 0.90 | DPP8 (0.37) | DPP8DPP7DPP9DPP4ACE | |
| SCHEMBL7275536 | 0.90 | DPP8 (0.36) | DPP8DPP7DPP9DPP4BACE1 | |
| SCHEMBL3373796 | 0.88 | KMT2A (0.35) | DPP8DPP7DPP9DPP4POLB | |
| SCHEMBL10882100 | 0.85 | DPP8 (0.40) | DPP8DPP7DPP9DPP4ACE | |
| SCHEMBL10885324 | 0.84 | HPGD (0.36) | DPP8DPP7DPP9DPP4ACE | |
| SCHEMBL3372065 | 0.84 | METAP2 (0.37) | DPP8DPP7DPP9DPP4 | |
| SCHEMBL7266833 | 0.83 | DPP8 (0.41) | DPP8DPP7DPP9DPP4OPRD1 | |
| SCHEMBL10825128 | 0.82 | ACE (0.39) | ACELMNASMN1; SMN2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8253497-A | — | — | None | — | — | JP | disclosed |
| EP-1679303-B1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | KANEKA CORP (JP) | 2010-09-15 | — | — | EP | disclosed |
| EP-1035131-B1 | PROCESS FOR THE PREPARATION OF N2 -(1(S)-CARBOXY-3-PHENYLPROPYL)-L-LYSYL-L-PROLINE | KANEKA CORP (JP) | 2006-11-22 | — | — | EP | disclosed |
| EP-1513868-B1 | PROCESS FOR THE PRODUCTION OF LISINOPRIL | EOS ECZACIBASI OZGUN KIMYASAL (TR) | 2006-08-09 | — | — | EP | disclosed |
| EP-1679303-A1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | Kaneka Corporation (JP) | 2006-07-12 | — | — | EP | disclosed |
| EP-0903337-B1 | PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES | KANEKA CORP (JP) | 2006-04-12 | — | — | EP | disclosed |
| EP-1035131-A1 | PROCESS FOR THE PREPARATION OF N2 -(1(S)-CARBOXY-3-PHENYLPROPYL)-L-LYSYL-L-PROLINE | KANEKA CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |
| EP-0903337-A1 | PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES | KANEKA CORPORATION (JP) | 1999-03-24 | — | — | EP | disclosed |
| JP-H08253497-A | PEPTIDE-TYPE COMPOUND | RICHTER GEDEON V G RT | 1996-10-01 | — | — | JP | disclosed |
| EP-0336368-B1 | N2-(1-carboxy-3-phenylpropyl)-L-lysine derivative and process of producing lysinopril using the compound | KANEGAFUCHI CHEMICAL IND (JP) | 1995-02-01 | — | — | EP | disclosed |