Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369565 | 0.84 | DPP8 (0.38) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL6619629 | 0.84 | DPP8 (0.38) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL3373796 | 0.82 | KMT2A (0.35) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL5551891 | 0.79 | DPP8 (0.36) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL3369358 | 0.75 | METAP2 (0.42) | METAP2TSHRALDH1A1EPHX1 | |
| SCHEMBL5351447 | 0.75 | METAP2 (0.42) | METAP2TSHRALDH1A1EPHX1 | |
| SCHEMBL3370863 | 0.73 | DPP8 (0.37) | DPP4DPP8EPHX1DPP9DPP7 | |
| SCHEMBL7275536 | 0.73 | DPP8 (0.36) | DPP4DPP8EPHX1DPP9DPP7 | |
| SCHEMBL3372067 | 0.73 | PEPD (0.39) | METAP2TSHRDPP4DPP8DPP9 | |
| SCHEMBL3369356 | 0.71 | TSHR (0.41) | METAP2TSHRALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679303-B1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | KANEKA CORP (JP) | 2010-09-15 | — | — | EP | disclosed |
| EP-1679303-A1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | Kaneka Corporation (JP) | 2006-07-12 | — | — | EP | disclosed |
| EP-0903337-B1 | PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES | KANEKA CORP (JP) | 2006-04-12 | — | — | EP | disclosed |
| EP-0903337-A1 | PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES | KANEKA CORPORATION (JP) | 1999-03-24 | — | — | EP | disclosed |