Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961215 | 0.79 | TSHR (1.00) | TSHRPPARDTP53TDP1ACHE | |
| SCHEMBL26483 | 0.79 | TSHR (1.00) | TSHRPPARDTP53TDP1ACHE | |
| SCHEMBL25291824 | 0.78 | TSHR (0.59) | TSHRPPARDTP53TDP1ACHE | |
| SCHEMBL2150701 | 0.77 | TSHR (0.65) | TSHRPPARDTP53TDP1ACHE | |
| SCHEMBL28492909 | 0.77 | TSHR (0.94) | TSHRPPARDTP53TDP1ACHE | |
| Ammonia Solution, Strong SCHEMBL27738152 | 0.77 | TSHR (0.94) | TSHRPPARDTP53TDP1ACHE | |
| SCHEMBL11745101 | 0.77 | TSHR (0.94) | TSHRPPARDTP53TDP1ACHE | |
| SCHEMBL31574613 | 0.77 | TSHR (0.94) | TSHRPPARDTP53TDP1ACHE | |
| SCHEMBL29034374 | 0.77 | TSHR (0.94) | TSHRPPARDTP53TDP1ACHE | |
| SCHEMBL4609885 | 0.76 | TSHR (0.50) | TSHRPPARDTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956696-B | Synthesis method of side chain adsorption type concrete superplasticizer | 北京工业大学 | 2021-06-04 | — | — | CN | claimed |
| CN-115732748-A | Phosphate flame-retardant gel electrolyte and preparation method thereof | 中国人民解放军军事科学院防化研究院 | 2023-03-03 | — | — | CN | disclosed |
| CN-109956696-B | Synthesis method of side chain adsorption type concrete superplasticizer | 北京工业大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-112142791-A | Alpha-fluoro-beta-carbonyl-diaryl phosphine oxide and synthetic method of enantioselective diversity thereof | 兰州大学 | 2020-12-29 | — | — | CN | disclosed |
| US-7649015-B2 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | GILEAD SCIENCES, INC. | 2007-01-11 | — | — | US | disclosed |
| EP-1711617-A1 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTICS COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005064008-A9 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS | GILEAD SCIENCES INC (US) | 2006-09-28 | — | — | WO | disclosed |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | GILEAD SCIENCES. INC. | 2005-10-27 | — | — | US | disclosed |
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. | 2005-09-22 | — | — | US | disclosed |
| WO-2005064008-A1 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| EP-1509537-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003090690-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | PPA1, PPME1, PNP | TSHR 4770/4885PPARD 4279/4885TP53 821/4885 |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | CES1, PNP, PGLS | TSHR 4748/4885PPARD 2507/4885TP53 2298/4885 |
| US-20070010489-A1 | Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds | PPA1, PNP, PPME1 | TSHR 4782/4885PPARD 4352/4885TP53 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.