Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL802038 | 0.98 | DHODH (0.78) | DHODHMAPTKDM4EKMT2AALOX15 | |
| SCHEMBL3365283 | 0.98 | DHODH (0.78) | DHODHMAPTKDM4EKMT2AALOX15 | |
| SCHEMBL3369761 | 0.97 | DHODH (0.76) | DHODHMAPTKDM4EKMT2AALOX15 | |
| SCHEMBL3369764 | 0.97 | DHODH (0.76) | DHODHMAPTKDM4EKMT2AALOX15 | |
| Lithium SCHEMBL3369335 | 0.88 | MAPT (0.76) | DHODHMAPTKDM4EKMT2AALOX15 | |
| SCHEMBL22624746 | 0.87 | MAPT (0.78) | DHODHMAPTKDM4EKMT2AALOX15 | |
| SCHEMBL28759220 | 0.86 | MAPT (0.76) | DHODHMAPTKDM4EKMT2AALOX15 | |
| SCHEMBL3365093 | 0.86 | MAPT (0.78) | DHODHMAPTKDM4EKMT2AALOX15 | |
| SCHEMBL803097 | 0.86 | MAPT (0.78) | DHODHMAPTKDM4EKMT2AALOX15 | |
| SCHEMBL3369332 | 0.84 | MAPT (0.76) | DHODHMAPTKDM4EKMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9437828-B2 | Electroluminescent device using azomethine-lithium-complex as electron injection layer | MERCK PATENT GMBH (DE) | 2016-09-06 | — | — | US | disclosed |
| US-20150065725-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| US-8883325-B2 | Electroluminescent device using azomethine-lithium-complex as electron injection layer | MERCK PATENT GMBH (DE) | 2014-11-11 | — | — | US | disclosed |
| US-20120205638-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | US | disclosed |
| US-20100327264-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATNET GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| EP-2095690-B1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GMBH (DE) | 2010-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120205638-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | ACSL3, APOL1, INTS9 | DHODH 3227/4885MAPT 3539/4885KDM4E 2810/4885 |
| US-20100327264-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | ACSL3, APOL1, INTS9 | DHODH 2974/4885MAPT 3581/4885KDM4E 2786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.