SCHEMBL336978

SCHEMBL336978

O=C(O)c1ccc(F)cc1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.65
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
ALDH1A1 P00352 6/20 0.48
CYP1A2 P05177 2/20 0.48
ALOX15 P16050 1/20 0.48
HSD17B10 Q99714 3/20 0.47
CDC25A P30304 1/20 0.47
CDC25B P30305 1/20 0.47
GAA P10253 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
HPGD P15428 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
USP2 O75604 1/20 0.46
DHFR P00374 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30520290 1.00 KEAP1 (0.65) KEAP1CES2CES1ALDH1A1CYP1A2
Boric Acid SCHEMBL29160824 0.93 KEAP1 (0.59) KEAP1CES2CES1ALDH1A1CYP1A2
SCHEMBL22343700 0.87 KEAP1 (0.57) KEAP1CES2CES1ALDH1A1CYP1A2
SCHEMBL1939097 0.87 KEAP1 (0.62) KEAP1CES2CES1ALDH1A1CYP1A2
SCHEMBL10961641 0.87 KEAP1 (0.62) KEAP1CES2CES1ALDH1A1CYP1A2
SCHEMBL28516694 0.87 KEAP1 (0.57) KEAP1CES2CES1ALDH1A1CYP1A2
SCHEMBL28473320 0.87 KEAP1 (0.57) KEAP1CES2CES1ALDH1A1CYP1A2
Ammonia Solution, Strong SCHEMBL11270732 0.85 KEAP1 (0.60) KEAP1CES2CES1ALDH1A1CYP1A2
Ammonia Solution, Strong SCHEMBL10961515 0.85 KEAP1 (0.60) KEAP1CES2CES1ALDH1A1CYP1A2
Ammonia Solution, Strong SCHEMBL10962367 0.85 KEAP1 (0.60) KEAP1CES2CES1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431706-A Fatigue-resistant polyurethane elastomer and preparation method and application thereof 万勋科技(深圳)有限公司 2025-02-14 CN claimed
CN-117209746-A Silane end capped polyether resin and preparation method and application thereof 江西蓝星星火有机硅有限公司 2023-12-12 CN claimed
CN-116555766-A Corrosion inhibitor for cooling liquid, preparation method of corrosion inhibitor and cooling liquid 深圳市英维克科技股份有限公司 2023-08-08 CN claimed
CN-113956454-B Phosphorus-nitrogen-fluorine flame-retardant oligomer, preparation method thereof, flame-retardant PBT (polybutylene terephthalate) polyester and preparation method thereof 中国石油化工股份有限公司 2023-06-09 CN claimed
CN-116063654-A Oil-resistant thermoplastic polyurethane elastomer and preparation method and application thereof 万华化学集团股份有限公司 2023-05-05 CN claimed
CN-114149575-B High-leveling and durable high-temperature-resistant polyester resin and preparation method thereof 黄山正杰新材料有限公司 2023-02-28 CN claimed
CN-112646149-B Lightweight low-dielectric-constant TPEE elastomer master batch and film preparation method 中国石油化工股份有限公司 2022-08-12 CN claimed
CN-112646326-B Preparation method of lightweight low-dielectric-constant PBT copolyester master batch and polyester film 中国石油化工股份有限公司 2022-08-09 CN claimed
CN-114149575-A High-leveling and durable high-temperature-resistant polyester resin and preparation method thereof 黄山正杰新材料有限公司 2022-03-08 CN claimed
CN-113956454-A Phosphorus-nitrogen-fluorine flame-retardant oligomer and preparation method thereof, flame-retardant PBT polyester and preparation method thereof 中国石油化工股份有限公司 2022-01-21 CN claimed
CN-112646148-A Weather-resistant low-dielectric-constant TPEE elastomer, and preparation method and application thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-112646149-A Lightweight low-dielectric-constant TPEE elastomer master batch and film preparation method 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-112646326-A Preparation method of lightweight low-dielectric-constant PBT copolyester master batch and polyester film 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-112646147-A Weather-proof PBT copolyester with low dielectric constant and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-112154169-A End-capped poly (aryl ether sulfone) polymers, poly (aryl ether sulfone) block copolymers and corresponding synthesis methods 索尔维特殊聚合物美国有限责任公司 2020-12-29 CN claimed
JP-62212189-A None JP disclosed
CN-122080034-A Polycyclic aromatic compound and organic electroluminescent element 2026-05-26 CN disclosed
US-4701396-A ELECTROSTATIC CHANGING, EXPOSURE TO PATTERN OF INFRARED RADIATION, AND DEVELOPMENT EASTMAN KODAK COMPANY (US) 1987-10-20 US disclosed
JP-S62212189-A THERMAL RECORDING MATERIAL KANZAKI PAPER MFG CO LTD 1987-09-18 JP disclosed
US-3956321-A REACT NITROPHTHALIC ANHYDRIDE WITH POTASSIUM FLUORIDE GENERAL ELECTRIC COMPANY (US) 1976-05-11 US disclosed