Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL10961515 | 1.00 | KEAP1 (0.60) | KEAP1CES2CES1DGAT1PARP1 | |
| SCHEMBL1939097 | 0.98 | KEAP1 (0.62) | KEAP1CES2CES1DGAT1PARP1 | |
| Ammonia Solution, Strong SCHEMBL10962367 | 0.92 | KEAP1 (0.60) | KEAP1CES2CES1DGAT1PARP1 | |
| SCHEMBL10961641 | 0.90 | KEAP1 (0.62) | KEAP1CES2CES1DGAT1PARP1 | |
| SCHEMBL29463969 | 0.87 | CES2 (0.52) | KEAP1CES2CES1DGAT1PARP1 | |
| SCHEMBL30520290 | 0.85 | KEAP1 (0.65) | KEAP1CES2CES1KDM4EHSD17B10 | |
| SCHEMBL336978 | 0.85 | KEAP1 (0.65) | KEAP1CES2CES1KDM4EHSD17B10 | |
| SCHEMBL7462377 | 0.79 | GAA (0.46) | KEAP1CES2CES1DGAT1PARP1 | |
| Boric Acid SCHEMBL29160824 | 0.79 | KEAP1 (0.59) | KEAP1CES2CES1KDM4EHSD17B10 | |
| SCHEMBL22343700 | 0.78 | KEAP1 (0.57) | KEAP1CES2CES1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055630-A2 | Method for the preparation of fluorophthalamic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1982-07-07 | — | — | EP | disclosed |