Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372258 | 0.84 | MAOB (0.45) | MEN1KMT2ATDP1MAOAMAOB | |
| SCHEMBL29522682 | 0.82 | MEN1 (0.52) | PGRPDK2PDK4MEN1KMT2A | |
| SCHEMBL1855552 | 0.82 | MEN1 (0.52) | PGRPDK2PDK4MEN1KMT2A | |
| SCHEMBL12997894 | 0.82 | MEN1 (0.52) | PGRPDK2PDK4MEN1KMT2A | |
| SCHEMBL12997896 | 0.82 | MEN1 (0.52) | PGRPDK2PDK4MEN1KMT2A | |
| SCHEMBL31638323 | 0.78 | PGR (0.46) | PGRPDK2PDK4MEN1KMT2A | |
| SCHEMBL28267013 | 0.78 | PGR (0.46) | PGRPDK2PDK4MEN1KMT2A | |
| SCHEMBL29141511 | 0.74 | PDK2 (0.39) | PGRIDO1PDK2PDK4MAOA | |
| SCHEMBL14490511 | 0.73 | MEN1 (0.37) | PGRMEN1KMT2ACDC25BKDM4E | |
| SCHEMBL29186770 | 0.73 | HTR2A (0.47) | PGRIDO1PDK2PDK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478616-B1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2010-09-22 | — | — | EP | claimed |
| EP-1478616-B1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2010-09-22 | — | — | EP | disclosed |
| US-7538243-B2 | Indanes and indanones and their use in perfumery | GIVAUDAN SA (CH) | 2009-05-26 | — | — | US | disclosed |
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | FLACHSMANN FELIX (CH) | 2005-07-07 | — | — | US | disclosed |
| EP-1478616-A1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | Givaudan SA (CH) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072533-A1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2003-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | NISCH, CYP1B1, CYP2E1 | PGR 798/4885IDO1 41/4885PDK2 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.