Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368845 | 0.79 | EGLN1 (0.57) | EGLN1EGLN3 | |
| SCHEMBL6427246 | 0.68 | AKR1B1 (0.62) | FTOEGLN2KMT2AMEN1KDM4E | |
| SCHEMBL3369852 | 0.67 | EGLN1 (0.71) | EGLN1POLBLMNAMAPTKDM4E | |
| SCHEMBL468296 | 0.66 | LMNA (0.65) | KMT2ALMNAMEN1MAPTKDM4E | |
| SCHEMBL29411993 | 0.66 | LMNA (0.65) | KMT2ALMNAMEN1MAPTKDM4E | |
| SCHEMBL19304783 | 0.65 | AKR1B1 (0.47) | FTOEGLN2KMT2ALMNAALDH1A1 | |
| SCHEMBL821706 | 0.63 | EGLN1 (0.41) | EGLN1FTOEGLN2EGLN3 | |
| SCHEMBL704958 | 0.62 | FTO (1.00) | EGLN1FTOEGLN2KDM5BKDM2A | |
| SCHEMBL30861597 | 0.62 | POLB (0.60) | FTOEGLN2KMT2APOLBLMNA | |
| SCHEMBL6426566 | 0.62 | POLB (0.60) | FTOEGLN2KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |