SCHEMBL3370264

SCHEMBL3370264

Oc1cc(Br)cc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.61
TRPM4 Q8TD43 1/20 0.58
CYP1A2 P05177 2/20 0.50
POLB P06746 1/20 0.48
CYP2A6 P11509 1/20 0.44
PTPN1 P18031 1/20 0.44
ALOX5 P09917 1/20 0.42
PTPN22 Q9Y2R2 1/20 0.41
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 2/20 0.41
HIF1A Q16665 1/20 0.41
CYP1B1 Q16678 1/20 0.41
PLAU P00749 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
RXFP1 Q9HBX9 1/20 0.41
ACP1 P24666 1/20 0.41
IDO1 P14902 1/20 0.40
MAOB P27338 1/20 0.40
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30447326 1.00 NQO2 (0.61) NQO2TRPM4CYP1A2POLBCYP2A6
SCHEMBL15998719 0.78 NQO2 (0.52) NQO2TRPM4CYP1A2POLBALOX5
SCHEMBL29524488 0.76 CYP2A6 (0.48) NQO2TRPM4CYP1A2POLBCYP2A6
SCHEMBL5147716 0.76 NQO2 (1.00) NQO2TRPM4CYP1A2PTPN1ALOX5
SCHEMBL8196720 0.76 NQO2 (0.67) NQO2TRPM4CYP1A2PTPN1ALOX5
SCHEMBL3103031 0.76 CYP2A6 (0.48) NQO2TRPM4CYP1A2POLBCYP2A6
SCHEMBL29434773 0.76 CYP2A6 (0.48) NQO2TRPM4CYP1A2POLBCYP2A6
SCHEMBL28681 0.76 NQO2 (1.00) NQO2TRPM4CYP1A2PTPN1ALOX5
SCHEMBL29351048 0.76 NQO2 (1.00) NQO2TRPM4CYP1A2PTPN1ALOX5
SCHEMBL774118 0.76 PLAU (0.59) NQO2CYP1A2CYP2A6PLAUMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250280650-A1 LIGHT EMITTING ELEMENT, FUSED POLYCYCLIC COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2025-09-04 US disclosed
CN-118791373-A Naphthalene-1 (2H) ketone derivative, preparation method thereof and application thereof in preparation of medicaments for promoting wound healing 广州市朝利良生物科技有限公司 2024-10-18 CN disclosed
CN-115572275-B Compound for organic optoelectronic device, composition for organic optoelectronic device, and display device 三星SDI株式会社 2024-07-26 CN disclosed
US-20230250109-A1 MACROCYCLIC ETHER CONTAINING INDOLE DERIVATIVES AS INHIBITORS OF MCL-1 JANSSEN PHARMACEUTICA NV (BE) 2023-08-10 US disclosed
US-20230250109-A1 MACROCYCLIC ETHER CONTAINING INDOLE DERIVATIVES AS INHIBITORS OF MCL-1 JANSSEN PHARMACEUTICA NV (BE) 2023-08-10 US disclosed
US-20230036794-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2023-02-02 US disclosed
CN-115572275-A Compound for organic optoelectronic device, composition for organic optoelectronic device, and display device 三星SDI株式会社 2023-01-06 CN disclosed
US-20210376241-A1 AMINE-SUBSTITUTED NAPHTHALENE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODES INCLUDING THE SAME SFC CO., LTD. (KR) 2021-12-02 US disclosed
CN-108250174-B Naphthopyran compounds and preparation method thereof 中国科学院兰州化学物理研究所苏州研究院 2021-09-10 CN disclosed
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
US-20030055265-A1 Oxazole derivatives HOFFMANN-LA ROCHE INC. 2003-03-20 US disclosed
WO-2002092084-A1 CARBOXYLIC ACID SUBSTITUTED OXAZOLE DERIVATIVES FOR USE AS PPAR-ALPHA AND -GAMMA ACTIVATORS IN THE TREATMENT OF DIABETES F. HOFFMANN-LA ROCHE AG (CH) 2002-11-21 WO disclosed
US-5629406-A AMINO ACID DERIVATIVES SANKYO COMPANY, LIMITED (JP) 1997-05-13 US disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed
US-4061642-A AZO DYE INTERMEDIATES CASSELLA FARBWERKE MAINKUR AG (DT) 1977-12-06 US disclosed
US-3980659-A INSECTICIDES, INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed
US-3956294-A AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3954782-A 2,6-Hydrazino-3-pyridine carboxyamides CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed
US-3947463-A Certain 2-amino-nicotinonitrile derivatives CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-30 US disclosed
US-3946024-A INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230036794-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OCIAD2, OXER1 NQO2 4195/4885TRPM4 50/4885CYP1A2 440/4885
US-20230250109-A1 MACROCYCLIC ETHER CONTAINING INDOLE DERIVATIVES AS INHIBITORS OF MCL-1 MCL1, BAK1, BCL2L1 NQO2 2002/4885TRPM4 3868/4885CYP1A2 3285/4885
US-20210376241-A1 AMINE-SUBSTITUTED NAPHTHALENE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODES INCLUDING THE SAME ARNT, SUN2, SLC7A5 NQO2 887/4885TRPM4 956/4885CYP1A2 451/4885
US-20030055265-A1 Oxazole derivatives PPARD, PPARA, PPARG NQO2 2094/4885TRPM4 1873/4885CYP1A2 1336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.