Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 8/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL27729028 | 0.91 | HSD17B1 (0.56) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL18529228 | 0.83 | CYP2A6 (0.45) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL30872049 | 0.83 | CTDSP1 (0.59) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL3982743 | 0.83 | CTDSP1 (0.59) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| Mequinol SCHEMBL5528621 | 0.82 | ESR2 (0.51) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL29364213 | 0.77 | HSD17B1 (0.70) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL29738652 | 0.77 | HSD17B1 (0.70) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL444105 | 0.77 | HSD17B1 (0.84) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL15451 | 0.77 | HSD17B1 (0.70) | PLAUHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL30457989 | 0.77 | CYP2A6 (0.52) | PLAUESR1ESR2CYP1A2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116135848-A | Coumarin compound and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2023-05-19 | — | — | CN | claimed |
| US-7211414-B2 | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity | VISIGEN BIOTECHNOLOGIES, INC. (US) | 2007-05-01 | — | — | US | claimed |
| US-4588833-A | CARBON MONOXIDE, ALCOHOL OR AMINE, ACID, UNSATURATED AMIDE, COBALTCOMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | claimed |
| EP-0143303-A2 | Process for the preparation of substituted succinic-acid amides | BAYER AG (DE) | 1985-06-05 | — | — | EP | claimed |
| US-20260078111-A1 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2026-03-19 | — | — | US | disclosed |
| EP-4630401-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | Rutgers, the State University of New Jersey (US) | 2025-10-15 | — | — | EP | disclosed |
| CN-119874527-A | Depsipeptide derivative, preparation method and application thereof | 常州工业职业技术学院 | 2025-04-25 | — | — | CN | disclosed |
| CN-119707930-A | Aromatic ring compound and its prepn and use | 甘李药业股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2024124023-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-06-13 | — | — | WO | disclosed |
| EP-4358948-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117865925-A | 3, 4-benzocoumarin compound based on complex functional aromatic hydrocarbon and preparation method and application thereof | 上海瑞苷生物科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-116135848-B | Coumarin compound and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2024-03-12 | — | — | CN | disclosed |
| US-4209593-A | Semi-flexible shock-absorbing polyurethane foam prepared from a triol, a compound having a single reactive hydrogen, an aromatic polyisocyanate, blowing agent, chain-extender and a catalyst | UNIROYAL LTD. (CA) | 1980-06-24 | — | — | US | disclosed |
| EP-0010842-A1 | Polyurethane foam and method of preparation thereof | UNIROYAL LTD. (CA) | 1980-05-14 | — | — | EP | disclosed |
| US-4061642-A | AZO DYE INTERMEDIATES | CASSELLA FARBWERKE MAINKUR AG (DT) | 1977-12-06 | — | — | US | disclosed |
| US-3980659-A | INSECTICIDES, INTERMEDIATES FOR AZO DYES | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |
| US-3956294-A | AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
| US-3954782-A | 2,6-Hydrazino-3-pyridine carboxyamides | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |
| US-3947463-A | Certain 2-amino-nicotinonitrile derivatives | CASSELLA FARBWERKE MAINKUR AG (DT) | 1976-03-30 | — | — | US | disclosed |
| US-3946024-A | INTERMEDIATES FOR AZO DYES | CASSELLA FARBWERKE MAINKUR AG (DT) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078111-A1 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | CA6, CA9, CA7 | PLAU 2040/4885HSD17B1 68/4885HSD17B2 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.