SCHEMBL3370447

SCHEMBL3370447

CCNc1ncc(C(F)(F)F)cc1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.63
POLB P06746 2/20 0.62
MEN1 O00255 6/20 0.58
KMT2A Q03164 6/20 0.58
HTT P42858 2/20 0.58
ALDH1A1 P00352 5/20 0.57
RAB9A P51151 4/20 0.57
LMNA P02545 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
JAK2 O60674 1/20 0.57
HSP90AA1 P07900 1/20 0.57
PKM P14618 1/20 0.57
MC4R P32245 1/20 0.57
CCR6 P51684 1/20 0.57
CACNA1B Q00975 1/20 0.57
APBA1 Q02410 1/20 0.57
TLR9 Q9NR96 1/20 0.57
SMN1; SMN2 Q16637 4/20 0.55
KDM4E B2RXH2 1/20 0.54
GAA P10253 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30149975 1.00 L3MBTL1 (0.63) L3MBTL1POLBMEN1KMT2AHTT
Hydrochloric Acid SCHEMBL28336950 0.98 L3MBTL1 (0.61) L3MBTL1POLBMEN1KMT2AHTT
Hydrochloric Acid SCHEMBL31427595 0.98 L3MBTL1 (0.61) L3MBTL1POLBMEN1KMT2AHTT
SCHEMBL13197581 0.87 POLB (0.67) L3MBTL1POLBMEN1KMT2AHTT
SCHEMBL15829430 0.85 L3MBTL1 (0.47) L3MBTL1POLBMEN1KMT2AHTT
SCHEMBL12315723 0.84 POLB (0.64) L3MBTL1POLBMEN1KMT2AHTT
SCHEMBL2006353 0.83 MEN1 (0.58) L3MBTL1POLBMEN1KMT2AHTT
SCHEMBL22809456 0.83 POLB (0.69) L3MBTL1POLBMEN1KMT2AHTT
SCHEMBL6676058 0.81 SMN1; SMN2 (0.59) L3MBTL1POLBMEN1KMT2AHTT
SCHEMBL31390547 0.81 SMN1; SMN2 (0.59) L3MBTL1POLBMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114031551-B Fluopicolide and synthesis method thereof 利民化学有限责任公司 2023-07-25 CN claimed
CN-114031551-A Fluopyram and synthesis method thereof 利民化学有限责任公司 2022-02-11 CN claimed
CN-111056997-A Synthetic method of benzamide compound 西安近代化学研究所 2020-04-24 CN claimed
CN-110437139-A A kind of synthetic method of fluopyram DALIAN JOIN KING FINE CHEMICAL CO LTD 2019-11-12 CN claimed
CN-115636764-B Synthesis method of benzamide compound 广东省科学院化工研究所 2024-03-12 CN disclosed
CN-114805188-B Fluopicolide synthesis method 利民化学有限责任公司 2023-11-21 CN disclosed
CN-114031551-B Fluopicolide and synthesis method thereof 利民化学有限责任公司 2023-07-25 CN disclosed
CN-115636764-A Synthetic method of benzamide compound 广东省科学院化工研究所 2023-01-24 CN disclosed
CN-114805188-A Fluopyram synthesis method 利民化学有限责任公司 2022-07-29 CN disclosed
CN-114031551-A Fluopyram and synthesis method thereof 利民化学有限责任公司 2022-02-11 CN disclosed
CN-111056997-A Synthetic method of benzamide compound 西安近代化学研究所 2020-04-24 CN disclosed
CN-110437139-A A kind of synthetic method of fluopyram DALIAN JOIN KING FINE CHEMICAL CO LTD 2019-11-12 CN disclosed
CN-110437139-A A kind of synthetic method of fluopyram DALIAN JOIN KING FINE CHEMICAL CO LTD 2019-11-12 CN disclosed
EP-1204642-B1 FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-10-13 EP disclosed
US-6939882-B1 Fungicides AVENTIS CROPSCIENCES GMBH (DE) 2005-09-06 US disclosed
CN-1185216-C Fungicidal agents AVENTIS CORPSCIENCE GMBH (DE) 2005-01-19 CN disclosed
CN-1372549-A Fungicidal agents AVENTIS CORPSCIENCE GMBH (DE) 2002-10-02 CN disclosed
EP-1204642-A1 FUNGICIDES Aventis CropScience GmbH (DE) 2002-05-15 EP disclosed
WO-2001012604-A1 FUNGICIDES AVENTIS CROPSCIENCE GMBH (DE) 2001-02-22 WO disclosed