Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MC4R | P32245 | 1/20 | 0.60 |
| ▸ | CCR6 | P51684 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13197581 | 0.86 | POLB (0.67) | POLBMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL22809623 | 0.84 | MEN1 (0.64) | POLBMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL12315723 | 0.84 | POLB (0.64) | POLBMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL648146 | 0.83 | MEN1 (0.63) | POLBMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL3370447 | 0.83 | L3MBTL1 (0.63) | POLBMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL30149975 | 0.83 | L3MBTL1 (0.63) | POLBMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL13970642 | 0.82 | POLB (0.62) | POLBMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL25057001 | 0.82 | ALDH1A1 (0.69) | POLBMEN1KMT2AHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL31427595 | 0.81 | L3MBTL1 (0.61) | POLBMEN1KMT2AHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28336950 | 0.81 | L3MBTL1 (0.61) | POLBMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | disclosed |