Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27034290 | 0.90 | FFAR4 (0.42) | HTTPOLBKMT2ALTA4HRXRA | |
| SCHEMBL13948753 | 0.82 | KMT2A (0.46) | SLC6A2SLC6A4KMT2ALTA4HRXRA | |
| SCHEMBL3730851 | 0.82 | UTS2R (0.44) | SLC6A2SLC6A4POLBKMT2AKDM4E | |
| SCHEMBL26488721 | 0.79 | TP53 (0.41) | KMT2AFFAR1LTA4H | |
| SCHEMBL10445124 | 0.78 | TAAR1 (0.41) | HTTSLC6A2SLC6A4KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL9553902 | 0.78 | TP53 (0.40) | KMT2AFFAR1LTA4H | |
| SCHEMBL27242802 | 0.78 | HDAC3 (0.42) | POLBKMT2ASIGMAR1ESR1 | |
| SCHEMBL2637695 | 0.76 | TP53 (0.47) | KMT2ALTA4H | |
| SCHEMBL10959342 | 0.74 | ALDH1A1 (0.46) | KMT2AHPGD | |
| SCHEMBL10959333 | 0.74 | ALDH1A1 (0.46) | KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | EXELIXIS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-4234483-A | COLORFASTNESS; BRIGHTNESS | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1980-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | S1PR1, S1PR5, S1PR3 | HTT 4253/4885SLC6A2 1200/4885SLC6A4 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.