SCHEMBL10445124

SCHEMBL10445124

CN(CCO)c1ccccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.41
MAPT P10636 3/20 0.41
GAA P10253 2/20 0.41
PKM P14618 1/20 0.41
HTT P42858 1/20 0.41
MCL1 Q07820 1/20 0.41
ALDH1A1 P00352 3/20 0.40
AOC3 Q16853 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ESR1 P03372 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
TACR1 P25103 1/20 0.36
TACR3 P29371 1/20 0.36
NTSR1 P30989 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5540709 0.80 TAAR1 (0.41) TAAR1AOC3ESR1SLC6A2SLC6A4
SCHEMBL4975914 0.79 KMT2A (0.47) TAAR1MAPTGAAPKMHTT
SCHEMBL3370588 0.78 HTT (0.44) HTTKDM4EESR1SLC6A2SLC6A4
SCHEMBL5164785 0.78 HSD17B10 (0.42) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL11702654 0.78 ALDH1A1 (0.45) MAPTGAAALDH1A1KDM4ESLC6A2
SCHEMBL5541885 0.77 TAAR1 (0.39) TAAR1AOC3ESR1SLC6A2SLC6A4
SCHEMBL6577756 0.77 SIGMAR1 (0.43) MAPTGAAHTTALDH1A1KDM4E
SCHEMBL11299548 0.77 MAPT (0.43) TAAR1MAPTGAAPKMHTT
SCHEMBL11131721 0.77 TAAR1 (0.41) TAAR1AOC3ESR1SLC6A2SLC6A4
SCHEMBL1230944 0.76 AOC3 (0.40) TAAR1MAPTGAAPKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0370953-A2 Process for the preparation of dye intermediates CIBA-GEIGY AG (CH) 1990-05-30 EP disclosed