SCHEMBL3370634

SCHEMBL3370634

N=C=O.NC(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9903394 1.00 LMNA (0.36)
SCHEMBL28121212 0.84
SCHEMBL28176962 0.84
Urea SCHEMBL2288083 0.84 LMNA (0.55)
Urea SCHEMBL10965886 0.84 LMNA (0.55)
Urea SCHEMBL5915116 0.84
SCHEMBL4592944 0.84
Urea SCHEMBL30336008 0.84 LMNA (0.55)
SCHEMBL20958648 0.81 CRBN (0.36)
SCHEMBL8392893 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4208441-B1 PROCESS FOR PRODUCING ISOCYANATES BASF SE (DE) 2024-06-26 EP disclosed
US-20230312462-A1 PROCESS FOR PRODUCING ISOCYANATES BASF SE (DE) 2023-10-05 US disclosed
EP-4208441-A1 PROCESS FOR PRODUCING ISOCYANATES BASF SE (DE) 2023-07-12 EP disclosed
CN-116034102-A Process for preparing isocyanates 巴斯夫欧洲公司 2023-04-28 CN disclosed
CN-109843952-A Polyisocyanate composition, blocked polyisocyanate composition, hydrophilic polyisocyanate composition, coating composition and coating film 旭化成株式会社 2019-06-04 CN disclosed
CN-109803993-A polyisocyanate mixture, coating composition and coating film 旭化成株式会社 2019-05-24 CN disclosed
CN-109311889-A Activin receptor-like kinase inhibitors 蓝图药品公司 2019-02-05 CN disclosed
EP-2060560-B1 Preparation of light-colored isocyanates COVESTRO DEUTSCHLAND AG (DE) 2016-04-13 EP disclosed
US-9024057-B2 Process for the preparation of isocyanates in the gas phase BAYER MATERIALSCIENCE AG (DE) 2015-05-05 US disclosed
US-20100152484-A1 PROCESS FOR THE PREPARATION OF ISOCYANATES IN THE GAS PHASE BAYER MATERIALSCIENCE AG (DE) 2010-06-17 US disclosed
US-20050075377-A1 PPAR compounds PFIZER INC 2005-04-07 US disclosed
US-6699904-B2 PEROXISOME PROLIFERATOR ACTIVATOR RECEPTOR (PPAR) AGONISTS; ATHEROSCLEROSIS AND CARDIOVASCULAR DISORDERS; FOR EXAMPLE, 3-(4-(2-(3-(2,4-DIMETHOXY-PHENYL)-1-HEPTYL-UREIDO)-ETHYL)-PHENYL)-2-ETHOXY -PROPIONIC ACID PFIZER INC. 2004-03-02 US disclosed
EP-1372632-A1 PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS Pfizer Products Inc. (US) 2004-01-02 EP disclosed
EP-1360172-A1 PPAR AGONISTS Pfizer Products Inc. (US) 2003-11-12 EP disclosed
US-20020169192-A1 PPAR compounds HAYWARD CHERYL M (US) 2002-11-14 US disclosed
US-20020165282-A1 Peroxisome proliferator activator receptor (PPAR) agonists; atherosclerosis and cardiovascular disorders; for example, 3-(4-(2-(3-(2,4-dimethoxy-phenyl)-1-heptyl-ureido)-ethyl)-phenyl)-2-ethoxy -propionic acid HAYWARD CHERYL M (US) 2002-11-07 US disclosed
WO-2002064549-A1 PPAR AGONISTS PFIZER PRODUCTS INC. (US) 2002-08-22 WO disclosed
WO-2002064130-A1 PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS PFIZER PRODUCTS INC. (US) 2002-08-22 WO disclosed
WO-2000047819-A1 SIZING DISPERSION AKZO NOBEL N.V. (NL) 2000-08-17 WO disclosed
US-4230845-A X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1980-10-28 US disclosed