Urea

Urea

SCHEMBL2288083

N=C=O.N=C=O.NC(N)=O

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
ALDH1A1 P00352 2/20 0.55
OR51E2 Q9H255 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ACHE P22303 1/20 0.39
BLM P54132 2/20 0.36
PMP22 Q01453 2/20 0.36
ALOX15 P16050 1/20 0.36
LDHA P00338 1/20 0.33
LDHB P07195 1/20 0.33
CYP3A4 P08684 2/20 0.31
TSHR P16473 2/20 0.31
NFKB1 P19838 2/20 0.31
HPGD P15428 1/20 0.31
EHMT2 Q96KQ7 1/20 0.31
HSD17B10 Q99714 1/20 0.31
EHMT1 Q9H9B1 1/20 0.31
CYP1A2 P05177 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL10965886 1.00 LMNA (0.55) LMNAALDH1A1OR51E2TDP1ACHE
Urea SCHEMBL5915116 1.00
Urea SCHEMBL30336008 1.00 LMNA (0.55) LMNAALDH1A1OR51E2TDP1ACHE
Urea SCHEMBL27583568 0.96
Urea SCHEMBL28144430 0.92
Urea SCHEMBL28254410 0.89
Urea SCHEMBL28223168 0.89 LMNA (0.43) LMNAALDH1A1OR51E2TDP1ACHE
Carbamic Acid SCHEMBL6382875 0.87
SCHEMBL30931519 0.87 LDHA (0.40) LMNAALDH1A1OR51E2TDP1ACHE
Carbamic Acid SCHEMBL20877106 0.87 ACHE (0.58) LMNAALDH1A1OR51E2TDP1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118374988-A Breathable thermochromic leather, preparation method thereof, heat dissipation assembly and application thereof 纾酷科技(深圳)有限公司 2024-07-23 CN claimed
US-11814360-B2 Isocyanates, derivatives, and processes for producing the same NOVOMER, INC. (US) 2023-11-14 US claimed
CN-113788923-B Curable photochromic compositions 光学转变公司 2023-07-28 CN claimed
CN-115894297-A Isocyanates, derivatives thereof and processes for their production 诺沃梅尔公司 2023-04-04 CN claimed
EP-4122597-A2 A PROCESS FOR PRODUCING A DIISOCYANATE PRODUCT, A PROCESS FOR PRODUCING AN AROMATIC ISOCYANATE PRODUCT AND A PROCESS FOR PRODUCING A POLYURETHANE PRODUCT Novomer, Inc. (US) 2023-01-25 EP claimed
WO-2022041885-A1 ELASTIC MATERIAL FOR 3D PRINTING AND PREPARATION METHOD THEREFOR, AND PRINTING METHOD AND DEVICE 珠海赛纳三维科技有限公司 2022-03-03 WO claimed
CN-113788923-A Curable photochromic compositions 光学转变公司 2021-12-14 CN claimed
CN-107922566-B Curable photochromic compositions 光学转变公司 2021-10-22 CN claimed
US-20200331876-A1 ISOCYANATES, DERIVATIVES, AND PROCESSES FOR PRODUCING THE SAME NOVOMER, INC. 2020-10-22 US claimed
EP-3691785-A1 ISOCYANATES, DERIVATIVES, AND PROCESSES FOR PRODUCING THE SAME Novomer, Inc. (US) 2020-08-12 EP claimed
EP-0042470-B1 THERMOSETTING MOULDING COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND THEIR USE IN A PROCESS FOR PREPARING MOULDED ARTICLES BAYER AG (DE) 1984-11-28 EP claimed
EP-0025992-B1 PROCESS FOR COATING GLASS SURFACES CHEMISCHE WERKE HÜLS AG (DE) 1983-09-07 EP claimed
EP-0025994-B1 PROCESS FOR COATING GLASS SURFACES CHEMISCHE WERKE HÜLS AG (DE) 1983-06-01 EP claimed
US-4340712-A Process for the preparation of polyisocyanates containing biuret and/or higher polyuret groups and use thereof as synthesis component in the preparation of polyurethane plastics BAYER AKTIENGESELLSCHAFT (DE) 1982-07-20 US claimed
US-4336180-A MOLDING MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1982-06-22 US claimed
EP-0012973-B1 PROCESS FOR THE PREPARATION OF BI- AND/OR POLYURET-POLYISOCYANATES; PRODUCTS OBTAINED BY THIS PROCESS AND THEIR USE IN THE PREPARATION OF POLYURETHANES BAYER AG (DE) 1981-07-15 EP claimed
US-4146723-A CHEMICAL AND TEMPERATURE RESISTANT BAYER AKTIENGESELLSCHAFT (DE) 1979-03-27 US claimed
US-4028306-A COATINGS BAYER AKTIENGESELLSCHAFT (DT) 1977-06-07 US claimed
US-3976622-A POLYURETHANES BAYER AKTIENGESELLSCHAFT (DT) 1976-08-24 US claimed
US-3943158-A POLYURETHANE MONOMERS BAYER AKTIENGESELLSCHAFT (DT) 1976-03-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200331876-A1 ISOCYANATES, DERIVATIVES, AND PROCESSES FOR PRODUCING THE SAME IDH1, IDH2, IDH3A LMNA 919/4885ALDH1A1 360/4885OR51E2 626/4885
US-11814360-B2 Isocyanates, derivatives, and processes for producing the same IDH1, IDH2, IDH3A LMNA 919/4885ALDH1A1 360/4885OR51E2 626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.