Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8291156 | 0.73 | HDAC1 (0.56) | HDAC1HDAC8HDAC6HDAC4HDAC3 | |
| SCHEMBL3366907 | 0.71 | HDAC1 (0.55) | HDAC1HDAC8HDAC6HDAC4HDAC3 | |
| SCHEMBL6526024 | 0.69 | L3MBTL1 (0.55) | L3MBTL1KDM4ELMNA | |
| SCHEMBL6533170 | 0.69 | L3MBTL1 (0.55) | L3MBTL1KDM4ELMNA | |
| SCHEMBL3370689 | 0.69 | HDAC1 (1.00) | HDAC1HDAC8 | |
| SCHEMBL3370672 | 0.69 | HDAC1 (1.00) | HDAC1HDAC8 | |
| SCHEMBL830718 | 0.69 | HDAC1 (0.48) | HDAC1HDAC8HDAC6HDAC4HDAC3 | |
| SCHEMBL3367582 | 0.69 | HDAC1 (0.58) | HDAC1HDAC8HDAC6HDAC4HDAC3 | |
| SCHEMBL3367586 | 0.69 | HDAC1 (0.58) | HDAC1HDAC8HDAC6HDAC4HDAC3 | |
| SCHEMBL8325372 | 0.68 | HDAC1 (0.58) | HDAC1HDAC8HDAC6HDAC4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673349-B1 | BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S BIO PTE LTD (SG) | 2010-06-30 | — | — | EP | claimed |