Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 6/20 | 0.48 |
| ▸ | FPR1 | P21462 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526024 | 1.00 | L3MBTL1 (0.55) | L3MBTL1KDM4ELMNAALDH1A1TSHR | |
| SCHEMBL598669 | 0.89 | LMNA (0.53) | L3MBTL1KDM4ELMNAALDH1A1TSHR | |
| SCHEMBL5100806 | 0.88 | L3MBTL1 (0.52) | L3MBTL1KDM4ELMNAALDH1A1TSHR | |
| SCHEMBL6528089 | 0.85 | NPSR1 (0.53) | L3MBTL1KDM4ELMNAALDH1A1TDP1 | |
| SCHEMBL27315337 | 0.85 | L3MBTL1 (0.69) | L3MBTL1KDM4ELMNAALDH1A1TSHR | |
| SCHEMBL5096849 | 0.85 | L3MBTL1 (0.50) | L3MBTL1KDM4ELMNAALDH1A1TSHR | |
| SCHEMBL5096847 | 0.85 | L3MBTL1 (0.50) | L3MBTL1KDM4ELMNAALDH1A1TSHR | |
| SCHEMBL5100623 | 0.83 | L3MBTL1 (0.48) | L3MBTL1KDM4ELMNAALDH1A1TSHR | |
| SCHEMBL5100444 | 0.83 | TDP1 (0.48) | L3MBTL1KDM4ELMNATDP1MEN1 | |
| SCHEMBL5100614 | 0.83 | L3MBTL1 (0.48) | L3MBTL1KDM4ELMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575925-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056784-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | WO | disclosed |