SCHEMBL3370914

SCHEMBL3370914

Cc1ccc(-c2nc(CI)c(C3CCCCC3)o2)cc1.Cc1ccc(-c2nc(COCCCOCc3cccc(C)c3C(=O)O)c(C3CCCCC3)o2)cc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
PPARG P37231 12/20 0.34
PPARA Q07869 12/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3292434 0.96 MEN1 (0.38) MEN1KMT2APPARGPPARAKDM4E
SCHEMBL3371224 0.85 PPARG (0.43) PPARGPPARAKDM4ETP53
SCHEMBL3373753 0.83 PPARG (0.38) PPARGPPARAKDM4ETP53
SCHEMBL3370847 0.83 PPARG (0.45) PPARGPPARAKDM4ETP53
SCHEMBL3368702 0.82 PPARA (0.41) PPARGPPARATP53
SCHEMBL3298881 0.82 PPARG (0.46) PPARGPPARAKDM4ETP53
SCHEMBL3292431 0.80 PPARG (0.41) PPARGPPARAKDM4ETP53
SCHEMBL3317048 0.80 PPARG (0.48) PPARGPPARAKDM4ETP53
SCHEMBL3314538 0.79 PPARA (0.44) PPARGPPARATP53
SCHEMBL3426842 0.78 PPARA (0.43) PPARGPPARATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1902039-B1 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS SANOFI AVENTIS (FR) 2010-10-13 EP disclosed
EP-1902039-A1 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS Sanofi-Aventis (FR) 2008-03-26 EP disclosed
WO-2007000235-A1 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS SANOFI-AVENTIS (DE) 2007-01-04 WO disclosed